ArticleJournal of the Pediatric Orthopaedic Society of North America2024
Fracture nonunion and delayed union.
Article in Journal of the Pediatric Orthopaedic Society of North America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Predictors of delayed union after surgical treatment in patients with osteoporotic vertebral compression fractures: a systematic review and meta-analysis.Journal of orthopaedic surgery and research · 2026Pooled it
- Injectable hydrogels for bone regeneration: from materials design to clinical translation.RSC advances · 2026Review
- Gunshot Wounds and Orthopaedic Injury at a Pediatric Level I Trauma Center.Journal of the Pediatric Orthopaedic Society of North America · 2026Article
- Article
- Functional mechanism and clinical implications of miR-455-5p in delayed fracture healing.Journal of orthopaedic surgery and research · 2025Article
- Clinical investigation of extracorporeal shock wave therapy combined with kinesitherapy on the treatment of delayed union of tibia and fibula fractures.American journal of translational research · 2025Article
- Investigating the Promising P28 Peptide-Loaded Chitosan/Ceramic Bone Scaffolds for Bone Regeneration.Molecules (Basel, Switzerland) · 2024Article
Corrections and comments
- Erratum issued
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Delayed union and nonunion of fractures exist in the pediatric population. Fracture healing requires the synergistic collaboration of mechanical support and robust biological processes to allow endochondral ossification, reestablishment of bone continuity, and subsequent remodeling to strong lamellar bone. Failure of either mechanical stability or biology may manifest as delayed fracture healing. While early recognition of potential metabolic and pharmacologic risk factors may be addressed by pre-emptive treatment using nutritional and vitamin D supplements, definitive treatment of established nonunion requires a comprehensive approach. Key Concepts: (1)Delayed unions and nonunions are more common in adult bone but can also occur in pediatric bone.(2)Fracture healing requires synergistic collaboration of mechanical support and robust biological processes; treatment of nonunions should address both the biological and mechanical factors.(3)Vitamin D is an integral component of calcium absorption and bone health.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.