Evidence map›Paper›PMID 40433280›Full record

ArticleJournal of the Pediatric Orthopaedic Society of North America2024

The role of bone health in low-velocity fractures and the effects of obesity on the growing skeleton.

Adam Kreutzer, Jessica McMichael, Philip Nowicki

Erratum issuedAbstract read
In one paragraph

Article in Journal of the Pediatric Orthopaedic Society of North America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Adam KreutzerDepartment of Orthopaedic Surgery, Riverside University Health System Medical Center, Moreno Valley, CA, USA.
Jessica McMichaelChildren's Hospital of Orange County, Orange, CA, USA.
Philip NowickiHelen DeVos Children's Hospital, Grand Rapids, MI, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vitamin D insufficiency in pediatric patients is common. Low levels of vitamin D affect bone mineralization, and in growing children, affect bone formation. This effect on overall bone health places children with vitamin D insufficiency and deficiency at risk for low-velocity fractures. Counseling pediatric patients on adequate vitamin D and calcium supplementation can decrease long-term bone health deficits and lead to improved health status as adults. In addition, obesity rates continue to increase in children. Obesity has direct effects on bone metabolism that negatively impact growing skeletons. Refined definitions for obesity will help prevent labeling patients inappropriately as obese but also allow physicians to counsel children and their parents on the long-term risks that obesity plays on both bone health and overall health. Key Concepts: (1)Vitamin D has a strong influence on bone health with low levels of vitamin D being associated with low bone mineralization on DEXA scans.(2)Children with low vitamin D are at risk for low-velocity fractures including the need for surgical intervention for these lower energy injuries.(3)Obesity leads to a chronic inflammatory state that creates a negative overall effect on the growing skeleton.(4)Obesity can be a stigmatizing condition resulting from many factors related to socioecological, environmental, and genetic influences but when appropriately addressed, can lead to improved long-term bone and overall health.

Indexed as

AdipocytesLeptinObesityRANKLVitamin-D insufficiency

Identifiers

PMID40433280
PMCPMC12088206

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.