Evidence map›Paper›PMID 40433186›Full record

ArticleIranian journal of medical sciences2025

Analysis of

Mahsa Hokmabadi, Elnaz Asadifard, Sepideh Arbabi-Bidgoli, Anoosh Naghavi, Mandana Hasanzad

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Iranian journal of medical sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mahsa HokmabadiMedical Genomic Research Center, Tehran Medical Sciences Islamic Azad University, Tehran, Iran.
Elnaz AsadifardMedical Genomic Research Center, Tehran Medical Sciences Islamic Azad University, Tehran, Iran.
Sepideh Arbabi-BidgoliDepartment of Toxicology and Pharmacology, Faculty of Pharmacy and Pharmaceutical Sciences, Islamic Azad University, Tehran Medical Sciences (IAUTMU), Tehran, Iran.
Anoosh NaghaviDepartment of Medical Genetics, School of Medicine, Zahedan University of Medical Sciences (ZAUMS), Zahedan, Iran.
Mandana HasanzadPersonalized Medicine Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The cytochrome P450 (P450s or CYPs) enzyme family, particularly Methods: Blood samples were obtained from 389 individuals across several ethnic groups in Tehran, Iran, from May to December 2022. PCR was used to amplify the region containing the desired variant. Genotyping was performed using the Sanger sequencing method. Results: Our analysis revealed a high frequency of normal alleles for all four studied variants, indicating the absence of the risk allele in the Iranian population. These findings suggest that the studied alleles have no apparent effect on various ethnic groups in Iran. Conclusion: The Iranian population has a typical genetic makeup for

Indexed as

Cytochrome P-450 CYP2D6Gene FrequencyAdultAllelesFemaleGenetic VariationGenotypeHumansIranMaleMiddle AgedPolymorphism, Single NucleotideCytochrome P-450 CYP2D6PharmacogeneticsPolymorphism, geneticPrecision medicine

Identifiers

PMID40433186
PMCPMC12104541

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.