Evidence map›Paper›PMID 40433150›Full record

ArticleFrontiers in plant science2025

Impact of codon optimization on

Shengyan Li, Ning Wen, Wenjie Lv, Mingjun Zhang, Yinxiao Wang, Zhihong Lang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in plant science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shengyan Li *Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing, China.
Ning Wen *Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing, China.
Wenjie LvBiotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing, China.
Mingjun ZhangBiotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing, China.
Yinxiao WangBiotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing, China.
Zhihong LangBiotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Codon optimization is critical for high expression of foreign genes in heterologous systems. The Methods and results: To develop insect-resistant maize, we designed two codon-optimized Discussion: These findings not only reveal the critical role of codon context in translation initiation and protein integrity but also provide a novel strategy for optimizing foreign genes in crop improvement, particularly offering valuable insights for engineering insect-resistant maize using Bt genes.

Indexed as

codon optimizationSpodoptera frugiperdasynonymous codon substitutiontransgenic maizetranslation initiationvip3Aa11 gene

Identifiers

PMID40433150
PMCPMC12106571

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.