ReviewInternational journal of nanomedicine2025
Advanced Strategies for Ultrasound Control and Applications in Sonogenetics and Gas Vesicle-Based Technologies: A Review.
Review in International journal of nanomedicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Engineering the next generation of cellular therapies for solid tumors: multi-specific armored CARs and TME reprogramming strategies.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026Review
- Application of ultrasound and ultrasound-responsive materials in wounds: A systematic review.International journal of pharmaceutics: X · 2026Review
- Sonogenetics for precision medicine: from molecular toolkit to clinical translation.Theranostics · 2026Review
- Ultrasound medicine in the era of precision theranostics: Mechanisms, molecular strategies, and clinical translation.Iranian journal of basic medical sciences · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Control systems play an important role in the diagnosis and treatment of medicine. In contrast to light and magnetic fields, ultrasound has received much attention due to its non-invasive, cost-effective, convenient, and high spatiotemporal precision and deep-penetration characteristics. Some studies have developed special nanomaterials for therapy by controlling the production of reactive oxygen species through ultrasound irradiation. However, the complex functionalities and toxicity issues associated with these nanomaterials limit the development of ultrasound control systems. To overcome these challenges, ultrasound control systems based on synthetic biology have been developed, especially for sonogenetics and gas vesicles. The tunable thermal and mechanical effects of ultrasound act as the main triggering source, enabling engineered cells to perform sono-thermal or sono-mechanical genetic modifications in the targeted tissue. Based on an in-depth understanding of the relationship between ultrasound effects and the design, composition, and applications of engineered cellular technologies, in this review, we focus on recent activation strategies of ultrasound for sonogenetics and gas vesicles, including sono-thermal promoter switch, sono-thermal transient receptor potential channel, sono-mechanical activation and gas vesicles. In addition, applications of these advanced ultrasound control systems for cancer therapy, neural activity, visual recovery and functional imaging are presented. Finally, we discuss the current challenges faced and provide an outlook on the future developments in this evolving field.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.