Evidence map›Paper›PMID 40433111›Full record

ArticleFood science & nutrition2025

Association Between ω-3, ω-6 Polyunsaturated Fatty Acid and Sleep Disorders: From Cross-Sectional to Mendelian Randomization Studies.

Lin Wang, Wei Quan, Jia Song, Yidan Qin, Huibin Zeng, Jian Zhang, Xuan Zhao, Jia Li, Jiajun Chen

Abstract read
In one paragraph

Article in Food science & nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Lin WangDepartment of Neurology China-Japan Union Hospital of Jilin University Changchun China.ORCID https://orcid.org/0000-0002-1232-6687
Wei QuanDepartment of Neurology China-Japan Union Hospital of Jilin University Changchun China.
Jia SongDepartment of Neurology China-Japan Union Hospital of Jilin University Changchun China.
Yidan QinDepartment of Neurology China-Japan Union Hospital of Jilin University Changchun China.
Huibin ZengDepartment of Neurology China-Japan Union Hospital of Jilin University Changchun China.
Jian ZhangDepartment of Neurology China-Japan Union Hospital of Jilin University Changchun China.
Xuan ZhaoDepartment of Neurology China-Japan Union Hospital of Jilin University Changchun China.
Jia LiDepartment of Neurology China-Japan Union Hospital of Jilin University Changchun China.
Jiajun ChenDepartment of Neurology China-Japan Union Hospital of Jilin University Changchun China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sleep disorders are a common health problem affecting a significant proportion of the adult population. Emerging evidence suggests that dietary factors, particularly polyunsaturated fatty acid (PUFA) intake, may play a role in modulating sleep quality. This study aims to investigate the association between omega-3 (ω-3) and omega-6 (ω-6) PUFA and sleep disorders using cross-sectional survey data and data from genome-wide association studies (GWAS). Using data from the National Health and Nutrition Examination Survey (NHANES, 2005-2018), we analyzed a cohort of 31,920 participants, with the primary independent variables being intake of ω-3 and ω-6 PUFAs. Multivariate regression was used to assess associations, and restricted cubic spline analysis was used to explore potential non-linear dose-response relationships. Two-sample Mendelian randomization (MR) analyses were performed to evaluate the causal effects of levels of multiple fatty acids on the risk of sleep disorders. For analysis on NHANES data, the participants with sleep disorders had significantly lower ω-3 PUFA intake (1.71 ± 1.11 g) compared to those without sleep disorders (1.78 ± 1.14 g,

Indexed as

mendelian randomizationNHANESomega‐3omega‐6polyunsaturated fatty acidssleep disorders

Identifiers

PMID40433111
PMCPMC12108440

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.