Evidence map›Paper›PMID 40433052›Full record

ArticleJournal of inflammation research2025

Clinical Characteristics of CARD14-Associated Papulosquamous Eruption and Evaluation of Therapeutic Efficacy of Secukinumab.

Xinrong Zhao, Zhaoyang Wang, Yunliu Chen, Xin Xiang, Yuanxiang Liu, Chaoyang Miao, Zigang Xu

Abstract read
In one paragraph

Article in Journal of inflammation research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xinrong ZhaoDepartment of Dermatology, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health and KeyLaboratory of Major Diseases in Children, Ministry of Education, Beijing, People's Republic of China.ORCID 0000-0003-2493-9031
Zhaoyang WangDepartment of Dermatology, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health and KeyLaboratory of Major Diseases in Children, Ministry of Education, Beijing, People's Republic of China.
Yunliu ChenDepartment of Dermatology, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health and KeyLaboratory of Major Diseases in Children, Ministry of Education, Beijing, People's Republic of China.ORCID 0000-0003-2259-6442
Xin XiangDepartment of Dermatology, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health and KeyLaboratory of Major Diseases in Children, Ministry of Education, Beijing, People's Republic of China.
Yuanxiang LiuDepartment of Dermatology, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health and KeyLaboratory of Major Diseases in Children, Ministry of Education, Beijing, People's Republic of China.
Chaoyang MiaoDepartment of Dermatology, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health and KeyLaboratory of Major Diseases in Children, Ministry of Education, Beijing, People's Republic of China.
Zigang XuDepartment of Dermatology, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health and KeyLaboratory of Major Diseases in Children, Ministry of Education, Beijing, People's Republic of China.ORCID 0000-0001-8645-1854

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Methods: We retrospectively analyzed a case series of 8 patients with CAPE in China. Whole-exome sequencing (WES) was performed in all patients to identify the mutation type. Three patients received the treatment of secukinumab with a 52-week follow-up period. They achieved 84.6%, 76.9%, and 68.8% improvement in PASI score, respectively. Results: The study identified three new variants in Conclusion: The mutation types in

Indexed as

biological treatmentsCARD14-associated papulosquamous eruptionCARD14 mutationsecukinumab

Identifiers

PMID40433052
PMCPMC12109596

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.