Evidence map›Paper›PMID 40432965›Full record

ArticleFrontiers in microbiology2025

Compound probiotics promote the growth of piglets through activating the JAK2/STAT5 signaling pathway.

Zhiyuan Li, Xueyan Dai, Fan Yang, Weina Zhao, Zhiwei Xiong, Wengen Wan, Guoyun Wu, Tianfang Xu, Huabin Cao

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. A ProbioticMicroorganisms · 2026
    Article
  4. Article
  5. Dietary supplementation withFrontiers in microbiology · 2026
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zhiyuan Li *Jiangxi Provincial Key Laboratory for Animal Health, Institute of Animal Population Health, College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang, China.
Xueyan Dai *Jiangxi Provincial Key Laboratory for Animal Health, Institute of Animal Population Health, College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang, China.
Fan YangJiangxi Provincial Key Laboratory for Animal Health, Institute of Animal Population Health, College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang, China.
Weina ZhaoJiangxi Agricultural Technology Extension Center, Nanchang, China.
Zhiwei XiongJiangxi Biotech Vocational College, Nanchang, Jiangxi, China.
Wengen WanJiangxi Agricultural Technology Extension Center, Nanchang, China.
Guoyun WuJiangxi Provincial Key Laboratory for Animal Health, Institute of Animal Population Health, College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang, China.
Tianfang XuJiangxi Agricultural Technology Extension Center, Nanchang, China.
Huabin CaoJiangxi Provincial Key Laboratory for Animal Health, Institute of Animal Population Health, College of Animal Science and Technology, Jiangxi Agricultural University, Nanchang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Composite probiotics are characterized by their non-resistance, no residues, non-toxic effects, and pollution-free nature. To investigate their application capability in piglets, this study aims to explore the effects of composite probiotics on the growth performance and related physiological indicators of piglets. Methods: Sixteen 30-day-old healthy weaned "Duroc × Landrace × Large White" piglets were randomly divided into a control group and a composite probiotic (CP) group. The CP group was supplemented with 2 mg·kg-1 of composite probiotics in the basal diet. After 120 days, the growth performance, serum biochemical parameters, hepatic hormones, and expression levels of JAK2/STAT5 signaling pathway-related factors were measured in each group. Results: The average daily gain of piglets in the CP group significantly increased, and the feed conversion ratio significantly decreased ( Discussion: In conclusion, composite probiotics effectively promote the growth performance of piglets by activating the JAK2/STAT5 signaling pathway. These findings provide a theoretical basis for the application of composite probiotics in piglet feeding.

Indexed as

compound probioticsgrowth performanceJAK2/STAT5 pathwayliverpiglet

Identifiers

PMID40432965
PMCPMC12107631

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.