Evidence map›Paper›PMID 40432751›Full record

ArticleBio-protocol2025

Electrophysiological Evaluation of a Sciatic Nerve Degree III Injury Model in Rats.

Linyu Chen, Ziyi Wang, Chengyao Wang, Ning Ma, Weiqin Zhao, Shuang Liu, Jiajun Lu, Boyuan Zhao, Hong Sun, Pengcheng Che and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bio-protocol, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Macrophage Dab1 Links Early Hypoxia to Adaptive Angiogenesis to Drive Peripheral Nerve Repair.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Linyu ChenCollege of Nursing and Rehabilitation, North China University of Science and Technology, Tangshan, China.
Ziyi WangCollege of Nursing and Rehabilitation, North China University of Science and Technology, Tangshan, China.
Chengyao WangCollege of Nursing and Rehabilitation, North China University of Science and Technology, Tangshan, China.
Ning MaSchool of Basic Medical Sciences, North China University of Science and Technology, Tangshan, China.
Weiqin ZhaoCollege of Nursing and Rehabilitation, North China University of Science and Technology, Tangshan, China.
Shuang LiuSchool of Basic Medical Sciences, North China University of Science and Technology, Tangshan, China.
Jiajun LuSchool of Basic Medical Sciences, North China University of Science and Technology, Tangshan, China.
Boyuan ZhaoCollege of Nursing and Rehabilitation, North China University of Science and Technology, Tangshan, China.
Hong SunSchool of Basic Medical Sciences, North China University of Science and Technology, Tangshan, China.
Pengcheng CheCollege of Nursing and Rehabilitation, North China University of Science and Technology, Tangshan, China.
Na DouCollege of Nursing and Rehabilitation, North China University of Science and Technology, Tangshan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sciatic nerve injury is a prevalent traumatic condition that significantly impacts a patient's quality of life. The sciatic nerve compression injury model is among the most commonly utilized models for investigating nerve repair and regeneration. Within this context, the degree III sciatic nerve injury model is frequently employed in scientific research due to its clinical relevance and its suitability for studies focused on functional recovery. However, a standardized approach for accurately assessing the success of constructing the degree III sciatic nerve injury model remains lacking. Traditional macroscopic observation methods exhibit limitations, whereas neurophysiological testing serves as a highly sensitive and objective evaluation technique that can directly reflect changes in nerve conduction function, thus providing reliable quantitative evidence for the successful establishment of the model. This study aims to offer a comprehensive description of the application of neurophysiological techniques in evaluating the construction of the degree III sciatic nerve injury model, thereby ensuring the success of model preparation. Key features • Precisely simulate a degree III sciatic nerve injury. • Conduct neurophysiological tests on the sciatic nerve 30 min after the injury. • Use neurophysiological techniques to improve the accuracy and repeatability of scientific study results.

Indexed as

Conduction velocityDegree III injuryModel constructionNeurophysiologySciatic nerve

Identifiers

PMID40432751
PMCPMC12104839

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.