Evidence map›Paper›PMID 40432647›Full record

ArticleCureus2025

Association Between Daily Mode of Transportation and Cognitive Function Among Older Adults With Mild Cognitive Impairment: A Cross-Sectional Observational Study.

Teruaki Masuda, Emiko Segawa, Noriyuki Kimura, Takuma Sato, Kenichi Anabuki, Yoshitaka Nakamura, Shigenobu Mitsuzawa, Satoru Shinkawa, Ken Aoshima, Etsuro Matsubara

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Driving the neural exposome: Latent mobility states from naturalistic GPS data in older adults.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Teruaki MasudaDepartment of Neurology, Faculty of Medicine, Oita University, Yufu, JPN.
Emiko SegawaHuman Biology Integration Foundation, Deep Human Biology Learning (DHBL), Eisai Co. Ltd Tsukuba Research Laboratories, Tsukuba, JPN.
Noriyuki KimuraDepartment of Neurology, Faculty of Medicine, Oita University, Yufu, JPN.
Takuma SatoHuman Biology Integration Foundation, Deep Human Biology Learning (DHBL), Eisai Co. Ltd Tsukuba Research Laboratories, Tsukuba, JPN.
Kenichi AnabukiHuman Biology Integration Foundation, Deep Human Biology Learning (DHBL), Eisai Co. Ltd, Bunkyo-ku, JPN.
Yoshitaka NakamuraHuman Biology Integration Foundation, Deep Human Biology Learning (DHBL), Eisai Co. Ltd Tsukuba Research Laboratories, Tsukuba, JPN.
Shigenobu MitsuzawaInnovative Research Excellence, Honda R & D Co. Ltd, Wako, JPN.
Satoru ShinkawaInnovative Research Excellence, Honda R & D Co. Ltd, Wako, JPN.
Ken AoshimaMicrobes & Host Defense Domain, Deep Human Biology Learning (DHBL), Eisai Co. Ltd Tsukuba Research Laboratories, Tsukuba, JPN.
Etsuro MatsubaraDepartment of Neurology, Faculty of Medicine, Oita University, Yufu, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background Changes in mode of transportation, such as driving cessation, elevate the risk of mild cognitive impairment (MCI) and Alzheimer's disease among older adults residing in communities. However, the association between transportation-related lifestyles and cognitive function in older adults with MCI remains unclear. This study aimed to explore the relationship between mobility independence and cognitive dysfunction among older patients with MCI. Methods This was a retrospective study of community-dwelling adults aged 65 years or older from Usuki, Oita Prefecture, Japan. Data from 117 participants with MCI were analyzed. Using the Lawton Instrumental Activities of Daily Living scale, participants were categorized into independent and dependent mobility groups based on their mode of transportation. Cognitive function was assessed using the Mini-Mental State Examination (MMSE) and the Japanese version of the Montreal Cognitive Assessment (MoCA-J), and scores were compared across modes of transportation. Results Significant differences were found in total MoCA-J scores, visuospatial executive function, naming, and orientation, and MMSE orientation of time and place, with higher scores observed in the independent mobility group compared to the dependent group (p < 0.05). Analysis of covariance further supported these findings, showing higher scores in total MoCA-J and MMSE scores in the independent mobility group. Conclusions This study highlights the relationship between daily mode of transportation and cognitive function in patients with MCI. Participants with independent mobility exhibited superior cognitive function compared to the dependent mobility group. These findings may contribute to the development of new interventions for preventing the transition from MCI to dementia by further validation of causal relationships in longitudinal or intervention studies.

Indexed as

alzheimer’s diseasecognitive functionmild cognitive impairmentmode of transportationpreventive care

Identifiers

PMID40432647
PMCPMC12107014

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.