Evidence map›Paper›PMID 40432638›Full record

ArticleCureus2025

Morphometric and Clinical Analysis of the Azygos Anterior Cerebral Artery: Insights From a Cadaveric Case Report Study.

Gervith Reyes Soto, Carlos Castillo-Rangel, Pablo Gonzalez-Lopez, Tshiunza Mpoyi Cherubin, Vladimir Nikolenko, Andreina Rosario Rosario, Amaya Alvarez Aquino, Iselle Suero Matos, Nasser M F El-Ghandour, Manuel De Jesus Encarnacion Ramirez

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Gervith Reyes SotoNeurosurgical Oncology, Mexico National Cancer Institute, Tlalpan, MEX.
Carlos Castillo-RangelNeurosurgery, Service of the 1ro de Octubre Hospital of the ISSSTE, Mexico City, MEX.
Pablo Gonzalez-LopezNeurosurgery, Hospital General Universitario de Alicante, Miguel Hernandez University, Alicante, ESP.
Tshiunza Mpoyi CherubinNeurosurgery, Clinique Ngaliema, Kinshasa, COD.
Vladimir NikolenkoHuman Anatomy and Histology, N.V. Sklifosovskiy Institute of Clinical Medicine, Moscow, RUS.
Andreina Rosario RosarioMedicine, Autonomous University of Santo Domingo (UASD), Santo Domingo, DOM.
Amaya Alvarez AquinoNeurotrauma and Global Neurosurgery, Foundation Meditech, Cali, COL.
Iselle Suero MatosMedicine, Instituto Tecnologico de Santo Domingo, Santo Domingo, DOM.
Nasser M F El-GhandourNeurosurgery, Faculty of Medicine, Cairo University, Cairo, EGY.
Manuel De Jesus Encarnacion RamirezNeurosurgery, Russian People's Friendship University, Moscow, RUS.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The azygos anterior cerebral artery (ACA) is an uncommon anatomical variation with important clinical implications. This study presents an in-depth morphometric analysis of a single brain specimen displaying this variant. The goal is to improve the understanding of its anatomical characteristics and its influence on cerebral vascular health. Through precise dissection and measurement, the study highlights the structural features of the azygos ACA and its potential role in clinical conditions, particularly in relation to aneurysm formation and associated risks. The brain specimen was sourced from the Laboratory of Microsurgical Anatomy of the Central Nervous System, Faculty of Medicine, National Autonomous University of Mexico (UNAM). The donor did not have a history of neurological disease or neurosurgical procedures, ensuring the integrity of the vascular structures for analysis. To facilitate analysis, red latex was injected into the specimen, which was then preserved in 10% formalin for two months. Morphometric assessments were carried out using a Mitutoyo Model CD-8" CX digital caliper with a resolution of 0.0005"/0.01mm, along with detailed photographic documentation. The study examined the brain of a 38-year-old male, which weighed 1,310 grams. Symmetry was observed in the A1 segments: the right A1 segment measured 11 mm in length and 3 mm in diameter, while the left A1 segment measured 10 mm in length and 2.4 mm in diameter. The anterior communicating artery (ACoA) was absent, and only a single A2 trunk was identified. This trunk had an initial diameter of 4 mm, which tapered to 3 mm over a length of 33 mm until it bifurcated. Common anatomical variations of the A1-ACoA complex include absence, bifurcation, hypoplasia, plexal arrangement, and fenestration. A thorough understanding of anterior cerebral circulation variants is essential for optimizing the treatment of vascular pathologies.

Indexed as

anterior cerebral arteryanterior communicating segmentazygosfronto-basal trunkneuroanatomy

Identifiers

PMID40432638
PMCPMC12107679

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.