Evidence map›Paper›PMID 40432631›Full record

ArticleCureus2025

HIV, Intussusception, and a Hidden Malignancy Masquerading Abdominal Tuberculosis: Diffuse Large B-Cell Lymphoma Unveiled.

Mitali Singh, Vaibhav Mane

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Mitali SinghPathology, Bharati Vidyapeeth (Deemed to be University) Medical College and Hospital, Sangli, IND.
Vaibhav ManePathology, Bharati Vidyapeeth (Deemed to be University) Medical College and Hospital, Sangli, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diffuse large B-cell lymphoma (DLBCL) is a common aggressive non-Hodgkin lymphoma, frequently seen in immunocompromised individuals. This report details the case of a 40-year-old HIV-positive female admitted for abdominal pain, vomiting, and imaging suggestive of disseminated tuberculosis, who was ultimately diagnosed with DLBCL of the ileum complicated by intussusception. Initial investigations revealed anemia and thrombocytosis. Contrast-enhanced CT showed multiple necrotic granulomatous lesions and jejunoileal intussusception, mimicking tuberculosis. Surgical exploration and resection of the intussuscepted ileal segment revealed a polypoidal tumor. Histopathological examination indicated a diffuse proliferation of lymphoma cells with plasmacytoid morphology. Immunohistochemistry confirmed DLBCL (germinal center B-cell subtype), with tumor cells positive for Oct-2, CD20, PAX5, BCL-6, and CD10 and negative for CD38, CD138, and MUM1. This case highlights the diagnostic challenges in differentiating intestinal DLBCL from infectious and inflammatory conditions such as tuberculosis in HIV-positive patients. It underscores the commentative role of biopsy and immunohistochemistry in accurate diagnosis and timely initiation of appropriate therapy, ultimately improving patient outcomes.

Indexed as

bcl6cd10 expressioncd20+diffuse large b cell lymphoma (dlbcl)disseminated tuberculosishiv lymphomaintussusception

Identifiers

PMID40432631
PMCPMC12108556

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.