SynthesisKorean journal of ophthalmology : KJO2025
The Efficacy of Sutureless Amnion Membrane Transplantation for Corneal Epithelialization in Delayed Corneal Healing: A Systematic Review.
Synthesis in Korean journal of ophthalmology : KJO, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Potential interference of the herpes simplex virus with periodontal regeneration: a narrative review.Clinical oral investigations · 2025Review
- Experimental Study of the Effect of Corneal Bio-Coating Based on the Original Hydrogel Biopolymer Scaffold on the Anterior Segment Structures of the Eye.Sovremennye tekhnologii v meditsine · 2025Article
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Authors and funding
2 authors.
Funding
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Abstract
purposeTo review the current evidence on the efficacy and safety of sutureless amniotic membrane transplantation (AMT) for promoting corneal epithelialization in delayed corneal healing disorders.
methodsA comprehensive search was conducted for studies published from January 2003 to December 2023. The inclusion criteria were studies that focused on delayed corneal healing (including persistent epithelial defect, dry eye disease, corneal ulcer, chemical injury, recalcitrant keratitis, or others), observed corneal re-epithelialization as the outcome, with the use of sutureless AM graft. Studies that reported sutureless AM combined with cyanoacrylate or fibrin glue were excluded.
resultsA total of 14 studies met the inclusion and exclusion criteria. The most common technique for sutureless AM on the cornea was self-retained cryopreserved AMT. The result of sutureless AMT in various delayed corneal healing disorders showed complete corneal epithelialization occurred in most patients (64.4%) which ranged from 3 to 43 days. There was a low rate of adverse events (pain, 2.9%; displaced AM or lost ring, 1.7%) and complications (sterile infiltrate, 1.8%; corneal perforation, 0.6%; ring trauma, 0.4%; central corneal scarring, 0.2%).
conclusionsSutureless AMT promotes complete corneal epithelialization. It is easier for multiple application, more comfortable, and has a lower risk of suture-related complications. Overall, sutureless AMT is effective and safe for a variety of corneal delayed healing disorders.
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