ArticleJournal of integrative plant biology2025
Cystatin-mediated enhancement of human epidermal growth factor bioproduction in plants.
Article in Journal of integrative plant biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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0 citing papers in PubMed.
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Authors and funding
8 authors.
Funding
Abstract
Human epidermal growth factor (EGF) fused with the protease inhibitor SlCYS8 and produced in plants showed enhanced stability, yield, and biological activity. This fusion strategy reduced degradation and outperformed commercial EGF in cell-based assays, demonstrating a promising approach for producing stable, functional proteins in plant systems for pharmaceutical applications.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.