Evidence map›Paper›PMID 40432453›Full record

ArticleRevista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia2025

Evolution of postsurgical mediastinitis after Major Heart Surgery (MHS) in the last 12 years: Are we improving?

María Jesús Pérez-Granda, Emilio Bouza, José María Barrio-Gutiérrez, Marina Machado, Agustín Estevez, Gregorio Cuerpo, Javier Hortal, Patricia Muñoz, Ángel González-Pinto, Maricela Valerio and 1 more

Abstract read
In one paragraph

Article in Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

María Jesús Pérez-GrandaClinical Microbiology and Infectious Diseases Department, Hospital General Universitario Gregorio Marañón, Madrid, Spain.ORCID 0000-0002-0613-2122
Emilio BouzaClinical Microbiology and Infectious Diseases Department, Hospital General Universitario Gregorio Marañón, Madrid, Spain.ORCID 0000-0001-6967-9267
José María Barrio-GutiérrezCIBER de Enfermedades Respiratorias-CIBERES (CB06/06/0058), Madrid, Spain.ORCID 0000-0002-7909-5342
Marina MachadoCIBER de Enfermedades Respiratorias-CIBERES (CB06/06/0058), Madrid, Spain.ORCID 0000-0002-8370-2248
Agustín EstevezCIBER de Enfermedades Respiratorias-CIBERES (CB06/06/0058), Madrid, Spain.
Gregorio CuerpoCIBER de Enfermedades Respiratorias-CIBERES (CB06/06/0058), Madrid, Spain.ORCID 0000-0002-8800-8423
Javier HortalCIBER de Enfermedades Respiratorias-CIBERES (CB06/06/0058), Madrid, Spain.ORCID 0009-0004-9929-7226
Patricia MuñozClinical Microbiology and Infectious Diseases Department, Hospital General Universitario Gregorio Marañón, Madrid, Spain.ORCID 0000-0001-5706-5583
Ángel González-PintoDepartment of Cardiac Surgery, Hospital General Universitario Gregorio Marañón, Madrid, Spain.ORCID 0009-0007-6959-7158
Maricela ValerioClinical Microbiology and Infectious Diseases Department, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
Cardiovascular Infection Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPostsurgical mediastinitis (PSM) is a serious and potentially life-threatening complication of Major Heart Surgery (MHS). Data on the evolution of the incidence of PSM after MHS in large series of operated patients in recent years are scarce. The aim of our study was to evaluate the trend of incidence, microbial etiology, and associated mortality of PSM at a referral MHS unit in the last 12 years. MATERIAL AND

methodsThe study was conducted at a tertiary hospital in Madrid, Spain. We carried out a retrospective and cross-sectional study that included all patients who underwent CCM and developed MPQ between January 2012 and December 2023 at our institution. It was conducted at a tertiary hospital in Madrid, Spain. We carried out a retrospective and cross-sectional study that included all patients who underwent CCM and developed MPQ between January 2012 and December 2023 at our institution.

resultsDuring the 12-year study period, a total of 5,584 patients underwent MHS at our institution. The incidence rate of PSM varied yearly between 1.16 and 2.34 episodes/100 surgical procedures. Overall, the 89 patients with PSM were analyzed (92 different episodes). Their median age was 67 years (IQR 56-75) and most of them were male (63%). Their median Euroscore was 7 (IQR 5-9.5). Main type of heart surgery in patients with PSM was: coronary artery bypass graft in 37% and valve replacement in 32.6%. The more frequent causative microorganisms were: Gram-positive bacteria (59.0%), Gram-negative bacteria (32.4%), fungi (7.6%) and others (1%). Overall, 22 patients died (24.7%).

conclusionsThe incidence of PSM has remained stable and below 2.5% in the last 12 years in our institution, but it continues to be an entity associated with high morbidity and mortality and long hospital stays.

Indexed as

Cardiac Surgical ProceduresMediastinitisPostoperative ComplicationsAgedCross-Sectional StudiesFemaleHumansIncidenceMaleMiddle AgedRetrospective StudiesSpainMajor heart surgeryMortalityPostsurgical mediastinitis

Identifiers

PMID40432453
PMCPMC12447299

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.