Evidence map›Paper›PMID 40432331›Full record

ArticleScience progress

Association between intracranial artery stenosis and aneurysm rupture risk: Proximal stenosis as a potential protective factor.

Yudi Tang, Jian Lv, Peike Chen, Junqiang Feng, Xiaoyan Wang, Dachao Wei, Siming Gui, Jia Jiang, Zhengkun Xu, Yan Zhao and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Science progress. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yudi TangDepartment of Interventional Neuroradiology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.ORCID 0000-0002-3436-7711
Jian LvDepartment of Interventional Neuroradiology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Peike ChenDepartment of Interventional Neuroradiology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Junqiang FengDepartment of Neurosurgery, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.
Xiaoyan WangDepartment of Biological Sciences, University of California, San Diego, California, USA.
Dachao WeiDepartment of Interventional Neuroradiology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.ORCID 0000-0003-3389-8112
Siming GuiDepartment of Interventional Neuroradiology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Jia JiangDepartment of Interventional Neuroradiology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Zhengkun XuSchool of Mechanical Engineering, Hebei University of Technology, Tianjin, China.ORCID 0009-0004-1229-1471
Yan ZhaoSchool of Mechanical Engineering, University of Science and Technology Beijing, Beijing, China.
Yuhua JiangDepartment of Interventional Neuroradiology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Youxiang LiDepartment of Interventional Neuroradiology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Peng LiuDepartment of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.ORCID 0009-0000-3413-2253

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ObjectiveParent artery and hemodynamics are related to intracranial aneurysms (IAs) rupture. Although proximal parent artery stenosis (PPAS) can both change parent artery configuration and hemodynamics, correlation between PPAS and IAs rupture has not been clearly clarified in large sample size. This study aims to explore the correlation between PPAS and IAs rupture in a large Chinese cohort.MethodsA retrospective cross-sectional study was conducted. Imaging and clinical data were collected from consecutive patients with IAs diagnosed by CTA between January 2013 and December 2022. Two neuroradiologists independently assessed the characteristics of the IAs. To minimize the effect of confounding variables, propensity score matching (PSM) was applied.ResultsAfter PSM, no significant differences were found between groups for interference factors. However, IAs in the PPAS group had a significantly lower proportion of ruptures compared to the non-PPAS group (p = 0.031). Additionally, unruptured aneurysms had a significantly higher prevalence of PPAS compared to ruptured aneurysms (p = 0.011). There was no significant difference in rupture rates between non-PPAS IAs with other intracranial artery stenosis (IAS) and those without IAS (p = 0.596). And ruptured non-PPAS IAs showed a significantly higher incidence of IAS compared to unruptured non-PPAS IAs (p = 0.010).ConclusionNon-PPAS may be associated with a higher risk of aneurysm rupture. In contrast, PPAS may be associated with unruptured aneurysm.

Indexed as

Aneurysm, RupturedIntracranial AneurysmAdultAgedConstriction, PathologicCross-Sectional StudiesFemaleHumansMaleMiddle AgedPropensity ScoreRetrospective StudiesRisk FactorsAneurysmaneurysm parent artery stenosisaneurysm ruptureartery stenosisrupture risk assessment

Identifiers

PMID40432331
PMCPMC12120314

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.