Evidence map›Paper›PMID 40432254›Full record

ArticleMolecular plant pathology2025

The Valsa mali Effector VmSR1 Accelerates the Degradation of Tudor-SN2 to Suppress RNA Silencing and Plant Immunity.

Tao Jiang, Chengli Wang, Mian Zhang, Yongli Qiao, Zhensheng Kang, Lili Huang

Abstract read
In one paragraph

Article in Molecular plant pathology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. The fungi effector VmRnt2 fromHorticulture research · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tao JiangState Key Laboratory for Crop Stress Resistance and High-Efficiency Production, College of Plant Protection, Northwest A&F University, Yangling, Shaanxi, China.
Chengli WangState Key Laboratory for Crop Stress Resistance and High-Efficiency Production, College of Plant Protection, Northwest A&F University, Yangling, Shaanxi, China.
Mian ZhangState Key Laboratory for Crop Stress Resistance and High-Efficiency Production, College of Plant Protection, Northwest A&F University, Yangling, Shaanxi, China.ORCID 0000-0003-2281-6724
Yongli QiaoShanghai Key Laboratory of Plant Molecular Sciences, College of Life Sciences, Shanghai Normal University, Shanghai, China.
Zhensheng KangState Key Laboratory for Crop Stress Resistance and High-Efficiency Production, College of Plant Protection, Northwest A&F University, Yangling, Shaanxi, China.
Lili HuangState Key Laboratory for Crop Stress Resistance and High-Efficiency Production, College of Plant Protection, Northwest A&F University, Yangling, Shaanxi, China.ORCID 0000-0002-7085-7646

Funding

Shaanxi Provincial Government F1020221012
6 · The paper itself

Abstract

The apple Valsa canker caused by Valsa mali is one of the most destructive trunk diseases in apple production and disease management. Understanding the interaction between the pathogen and host is a critical foundation for developing durable disease control technologies. In this study, we showed that VmSR1 from V. mali can suppress the plant immune response and promote pathogen infection. VmSR1 associates with the Tudor staphylococcal nuclease 2 (TSN2) proteins in Malus domestica (apple), Arabidopsis thaliana and Nicotiana benthamiana, promotes degradation of TSN2 proteins, and suppresses the abundance of multiple miRNAs an Silencing of TSN2 significantly reduced the abundance of miRNAs and weakened the resistance of apple leaves to V. mali as well as N. benthamiana to Sclerotinia sclerotiorum. These findings expand the understanding of the function of effectors as RNA silencing suppressors during host-pathogen interactions and deepen the understanding of effectors regulating host immunity.

Indexed as

AscomycotaMalusPlant DiseasesPlant ImmunityPlant ProteinsRNA InterferenceArabidopsisGene Expression Regulation, PlantHost-Pathogen InteractionsMicroRNAsNicotianaMicroRNAsPlant ProteinsapplemiRNARNA silencing suppressorsTudor‐SNValsa mali

Identifiers

PMID40432254
PMCPMC12116935

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.