Evidence map›Paper›PMID 40432141›Full record

ReviewVaccines2025

Development of New Live-Attenuated Vaccine Candidates Lacking Antibody-Dependent Enhancement (ADE) Against Dengue.

Brandon E K Tan, Seng Kong Tham, Chit Laa Poh

Abstract readReview
In one paragraph

Review in Vaccines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Antiviral agents for dengue virus.Virologica Sinica · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Brandon E K TanALPS Global Holding Berhad, The Icon, East Wing Tower Level 18-01 & Level 18-02, No. 1 Jalan 1/68F, Off Jalan Tun Razak, Kuala Lumpur 50400, Malaysia.ORCID 0000-0002-4586-6081
Seng Kong ThamALPS Global Holding Berhad, The Icon, East Wing Tower Level 18-01 & Level 18-02, No. 1 Jalan 1/68F, Off Jalan Tun Razak, Kuala Lumpur 50400, Malaysia.
Chit Laa PohALPS Global Holding Berhad, The Icon, East Wing Tower Level 18-01 & Level 18-02, No. 1 Jalan 1/68F, Off Jalan Tun Razak, Kuala Lumpur 50400, Malaysia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dengue virus (DENV) threatens public health, especially in regions with tropical and subtropical climates. In 2024, the World Health Organisation reported 3.4 million confirmed dengue cases, with 16,000 severe cases and 3000 dengue-associated fatalities. The first licensed dengue vaccine, CYD-TDV (Dengvaxia

Indexed as

amino acid residueantibody-dependent enhancementattenuationdenguelive-attenuated vaccinemutagenesis

Identifiers

PMID40432141
PMCPMC12115996

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.