Evidence map›Paper›PMID 40432139›Full record

ArticleVaccines2025

A Luciferase-Based Approach for Functional Screening of 5' and 3' Untranslated Regions of the mRNA Component for mRNA Vaccines.

Maria Rubtsova, Yuliana Mokrushina, Dmitry Andreev, Maria Poteshnova, Nikita Shepelev, Mariya Koryagina, Ekaterina Moiseeva, Diana Malabuiok, Yury Prokopenko, Stanislav Terekhov and 6 more

Abstract read
In one paragraph

Article in Vaccines, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Maria RubtsovaShemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Science, 117997 Moscow, Russia.
Yuliana MokrushinaShemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Science, 117997 Moscow, Russia.ORCID 0000-0002-4669-9545
Dmitry AndreevShemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Science, 117997 Moscow, Russia.
Maria PoteshnovaDepartment of Chemistry, Lomonosov Moscow State University, 119991 Moscow, Russia.
Nikita ShepelevDepartment of Chemistry, Lomonosov Moscow State University, 119991 Moscow, Russia.ORCID 0000-0002-5033-360X
Mariya KoryaginaDepartment of Chemistry, Lomonosov Moscow State University, 119991 Moscow, Russia.
Ekaterina MoiseevaShemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Science, 117997 Moscow, Russia.
Diana MalabuiokShemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Science, 117997 Moscow, Russia.ORCID 0009-0005-7740-282X
Yury ProkopenkoShemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Science, 117997 Moscow, Russia.ORCID 0000-0002-2603-5506
Stanislav TerekhovShemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Science, 117997 Moscow, Russia.ORCID 0000-0003-2220-0452
Aleksander ChernovShemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Science, 117997 Moscow, Russia.ORCID 0000-0001-5371-1656
Elena VodovozovaShemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Science, 117997 Moscow, Russia.ORCID 0000-0003-0164-7423
Ivan SmirnovShemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Science, 117997 Moscow, Russia.ORCID 0000-0002-0384-6568
Olga DontsovaShemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Science, 117997 Moscow, Russia.
Alexander GabibovShemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Science, 117997 Moscow, Russia.
Yury RubtsovShemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Science, 117997 Moscow, Russia.ORCID 0000-0001-9175-3013

Funding

Ministry of Science and Higher Education of Russian Federation Agreement #075-15-2021-1049
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

immunizationlipid nanoparticlesmRNA vaccineSARS-CoV-2secreted nanoluciferaseS proteintranslationUTRs

Identifiers

PMID40432139
PMCPMC12115628

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.