Evidence map›Paper›PMID 40431725›Full record

ArticleViruses2025

HIV-HPV Co-Infection and Identification of Novel High-Risk HPV Among Women at Two Hospital Centers in Cotonou, Republic of Benin.

Clémence D Gouton, Ifeoluwa O Bejide, Oludayo O Ope-Ewe, Marius Adjagba, Simon Azonbakin, Gaonyadiwe Muzanywa, Florence T Akinyi, Arnaud Agbanlinsou, Yanique Goussanou, Onikepe Folarin and 3 more

Abstract read
In one paragraph

Article in Viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Clémence D GoutonThe Africa Centre of Excellence for Genomics of Infectious Diseases (ACEGID), Redeemer's University Nigeria, Ede PMB 230, Nigeria.
Ifeoluwa O BejideThe Africa Centre of Excellence for Genomics of Infectious Diseases (ACEGID), Redeemer's University Nigeria, Ede PMB 230, Nigeria.ORCID 0000-0002-8263-9064
Oludayo O Ope-EweThe Africa Centre of Excellence for Genomics of Infectious Diseases (ACEGID), Redeemer's University Nigeria, Ede PMB 230, Nigeria.
Marius AdjagbaLaboratory of Histology-Reproductive Biology, Cytogenetics and Medical Genetics, Human Biology Unit, Faculty of Health Sciences, Abomey-Calavi University, Cotonou 01 BP 188, Benin.
Simon AzonbakinLaboratory of Histology-Reproductive Biology, Cytogenetics and Medical Genetics, Human Biology Unit, Faculty of Health Sciences, Abomey-Calavi University, Cotonou 01 BP 188, Benin.
Gaonyadiwe MuzanywaThe Africa Centre of Excellence for Genomics of Infectious Diseases (ACEGID), Redeemer's University Nigeria, Ede PMB 230, Nigeria.
Florence T AkinyiThe Africa Centre of Excellence for Genomics of Infectious Diseases (ACEGID), Redeemer's University Nigeria, Ede PMB 230, Nigeria.
Arnaud AgbanlinsouLaboratory of Histology-Reproductive Biology, Cytogenetics and Medical Genetics, Human Biology Unit, Faculty of Health Sciences, Abomey-Calavi University, Cotonou 01 BP 188, Benin.
Yanique GoussanouLaboratory of Histology-Reproductive Biology, Cytogenetics and Medical Genetics, Human Biology Unit, Faculty of Health Sciences, Abomey-Calavi University, Cotonou 01 BP 188, Benin.
Onikepe FolarinThe Africa Centre of Excellence for Genomics of Infectious Diseases (ACEGID), Redeemer's University Nigeria, Ede PMB 230, Nigeria.ORCID 0000-0001-7283-2920
Anatole LaleyeLaboratory of Histology-Reproductive Biology, Cytogenetics and Medical Genetics, Human Biology Unit, Faculty of Health Sciences, Abomey-Calavi University, Cotonou 01 BP 188, Benin.
Christian T HappiThe Africa Centre of Excellence for Genomics of Infectious Diseases (ACEGID), Redeemer's University Nigeria, Ede PMB 230, Nigeria.ORCID 0000-0002-3056-6705
Chinedu A UgwuThe Africa Centre of Excellence for Genomics of Infectious Diseases (ACEGID), Redeemer's University Nigeria, Ede PMB 230, Nigeria.ORCID 0000-0002-6347-1593

Funding

Gates Foundation ARISE- INV-036304World Bank ACE-019 and ACE-IMPACT
6 · The paper itself

Abstract

Persistent high-risk human papillomaviruses (HR-HPVs) infection is the leading cause of cervical cancer. With over 200 circulating genotypes, HPV detection, management, and prevention remain challenging. In Benin, HPV prevalence and genotype distribution are largely unknown, and no national HPV vaccination program exists. This study investigates the prevalence, genotypic diversity, and risk factors of HIV-HPV co-infection among women in Cotonou, Benin. Cervical swabs were collected from 100 women living with HIV (WLWHIV) and 51 women without HIV (WWHIV) at two hospitals. DNA extraction and nested polymerase chain reaction (PCR) were used to detect HPV, followed by Sanger sequencing for genotyping. Chi-squared analysis was used to assess risk factors. HPV was detected in 85% (85/100) of WLWHIV and 60.8% (31/51) of WWHIV (

Indexed as

CoinfectionHIV InfectionsPapillomaviridaePapillomavirus InfectionsAdultBeninDNA, ViralFemaleGenotypeHospitalsHumansMiddle AgedPhylogenyPrevalenceRisk FactorsYoung AdultDNA, Viralcervical cancerHIVHPV–HIV co-infectionhuman papillomavirus (HPV)prevalencerisk factorsSanger sequencing

Identifiers

PMID40431725
PMCPMC12115566

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.