Evidence map›Paper›PMID 40431688›Full record

ArticleViruses2025

Survey and Associated Risk Factors for the Presence of Ruminant Pestiviruses in Domestic Ovine and Caprine Populations from Kazakhstan.

Andrey V Zhigailov, Yuliya V Perfilyeva, Angelina A Malysheva, Alena S Cherusheva, Zhanna A Berdygulova, Dinara A Naizabayeva, Karina R Ivanova, Saltanat A Kuatbekova, Zhaniya M Dosmagambet, Anzhelika V Lushova and 15 more

Abstract read
In one paragraph

Article in Viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Viruses · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Andrey V ZhigailovAlmaty Branch of the National Center for Biotechnology, National Holding "QazBioPharm", 14 Zhahanger St., Almaty 050054, Kazakhstan.ORCID 0000-0002-9646-033X
Yuliya V PerfilyevaAlmaty Branch of the National Center for Biotechnology, National Holding "QazBioPharm", 14 Zhahanger St., Almaty 050054, Kazakhstan.
Angelina A MalyshevaAlmaty Branch of the National Center for Biotechnology, National Holding "QazBioPharm", 14 Zhahanger St., Almaty 050054, Kazakhstan.
Alena S CherushevaAlmaty Branch of the National Center for Biotechnology, National Holding "QazBioPharm", 14 Zhahanger St., Almaty 050054, Kazakhstan.
Zhanna A BerdygulovaAlmaty Branch of the National Center for Biotechnology, National Holding "QazBioPharm", 14 Zhahanger St., Almaty 050054, Kazakhstan.ORCID 0000-0003-0379-2472
Dinara A NaizabayevaAlmaty Branch of the National Center for Biotechnology, National Holding "QazBioPharm", 14 Zhahanger St., Almaty 050054, Kazakhstan.ORCID 0000-0002-0606-4289
Karina R IvanovaAlmaty Branch of the National Center for Biotechnology, National Holding "QazBioPharm", 14 Zhahanger St., Almaty 050054, Kazakhstan.ORCID 0000-0002-6096-2880
Saltanat A KuatbekovaAlmaty Branch of the National Center for Biotechnology, National Holding "QazBioPharm", 14 Zhahanger St., Almaty 050054, Kazakhstan.
Zhaniya M DosmagambetAlmaty Branch of the National Center for Biotechnology, National Holding "QazBioPharm", 14 Zhahanger St., Almaty 050054, Kazakhstan.
Anzhelika V LushovaAlmaty Branch of the National Center for Biotechnology, National Holding "QazBioPharm", 14 Zhahanger St., Almaty 050054, Kazakhstan.
Sofiya A KanAlmaty Branch of the National Center for Biotechnology, National Holding "QazBioPharm", 14 Zhahanger St., Almaty 050054, Kazakhstan.
Artyom V KuliginAlmaty Branch of the National Center for Biotechnology, National Holding "QazBioPharm", 14 Zhahanger St., Almaty 050054, Kazakhstan.
Akerke O BissenbayAlmaty Branch of the National Center for Biotechnology, National Holding "QazBioPharm", 14 Zhahanger St., Almaty 050054, Kazakhstan.ORCID 0000-0002-7109-2534
Moldir M KuatbekAlmaty Branch of the National Center for Biotechnology, National Holding "QazBioPharm", 14 Zhahanger St., Almaty 050054, Kazakhstan.
Akzhigit S MashzhanAlmaty Branch of the National Center for Biotechnology, National Holding "QazBioPharm", 14 Zhahanger St., Almaty 050054, Kazakhstan.ORCID 0000-0002-9516-5566
Nurshat AbdollaAlmaty Branch of the National Center for Biotechnology, National Holding "QazBioPharm", 14 Zhahanger St., Almaty 050054, Kazakhstan.
Anna S NizkorodovaAlmaty Branch of the National Center for Biotechnology, National Holding "QazBioPharm", 14 Zhahanger St., Almaty 050054, Kazakhstan.
Elina R MaltsevaAlmaty Branch of the National Center for Biotechnology, National Holding "QazBioPharm", 14 Zhahanger St., Almaty 050054, Kazakhstan.
Aralbek S RsaliyevNational Holding "QazBioPharm", 13/1 Walikhanov St., Astana 010000, Kazakhstan.
Yergali O AbduraimovNational Holding "QazBioPharm", 13/1 Walikhanov St., Astana 010000, Kazakhstan.
Ainur A ZhaksylykovaKazakh Scientific Research Veterinary Institute, National Holding "QazBioPharm", 223 Raiymbek Avenue, Almaty 050016, Kazakhstan.ORCID 0000-0001-8980-8804
Aida M AbdybekovaKazakh Scientific Research Veterinary Institute, National Holding "QazBioPharm", 223 Raiymbek Avenue, Almaty 050016, Kazakhstan.
Seidigapbar M MamadaliyevAlmaty Branch of the National Center for Biotechnology, National Holding "QazBioPharm", 14 Zhahanger St., Almaty 050054, Kazakhstan.
Yuriy A SkibaAlmaty Branch of the National Center for Biotechnology, National Holding "QazBioPharm", 14 Zhahanger St., Almaty 050054, Kazakhstan.
Yekaterina O OstapchukAlmaty Branch of the National Center for Biotechnology, National Holding "QazBioPharm", 14 Zhahanger St., Almaty 050054, Kazakhstan.ORCID 0000-0002-3771-423X

Funding

Science Committee of the Ministry of Science and Higher Education of the Republic of Kazakhstan STP No BR218004/0223
6 · The paper itself

Abstract

Pestiviruses, particularly bovine viral diarrhea virus (BVDV), cause significant economic losses worldwide. While cattle are the primary hosts for BVDV, sheep and goats can also be affected. This nationwide survey aimed to assess the prevalence, genetic characteristics, and risk factors associated with pestiviruses in sheep and goats in Kazakhstan. A one-off cross-sectional study was conducted to estimate the prevalence of pestiviruses in sheep and goats across 58 districts in 17 oblasts of Kazakhstan. A total of 2028 animals were examined using antibody ELISA, and RT-qPCR was performed on 2056 samples. Logistic regression models were used to identify potential risk factors linked to pestiviral infection. The overall prevalence of pestiviral infection in small ruminants was estimated to be 53.7% by ELISA and 2.5% by RT-qPCR. Regression analysis revealed that age, farm type, and geographic location were risk factors for pestiviral infections in small ruminants in Kazakhstan. Partial sequence analysis of the 5'-untranslated region confirmed the presence of BVDV2. Phylogenetic analysis revealed two distinct clusters of Kazakhstani BVDV2 strains, which were significantly different from known BVDV2 genotypes. No other ruminant pestiviruses were identified. The results highlight the importance of integrating small ruminants into BVDV infection control strategies to mitigate risks to livestock.

Indexed as

Goat DiseasesPestivirusPestivirus InfectionsSheep DiseasesAnimalsAntibodies, ViralCross-Sectional StudiesGoatsKazakhstanPhylogenyPrevalenceRisk FactorsSheepAntibodies, ViralBDVborder diseasebovine viral diarrheaBVDVKazakhstanPestivirusrisk analysissmall ruminants

Identifiers

PMID40431688
PMCPMC12115794

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.