Evidence map›Paper›PMID 40431642›Full record

ArticleViruses2025

Dynamics of Clinical, Radiological, and Biological Expression in Hospitalised COVID-19 Patients and Post-Infectious Mortality: Comparison Between 2024 and 2020.

Constantin-Marinel Vlase, Alina Plesea-Condratovici, Anca-Adriana Arbune, Roxana-Elena Goroftei-Bogdan, Cristian Gutu, Manuela Arbune

Abstract readComparative Study
In one paragraph

Article in Viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Constantin-Marinel VlaseMedical Clinic Department, Dunarea de Jos University, 800008 Galati, Romania.ORCID 0000-0002-0081-2856
Alina Plesea-CondratoviciMedical Department, Dunarea de Jos University, 800008 Galati, Romania.
Anca-Adriana ArbuneNeurology Department, Fundeni Clinical Institute, 077086 Bucharest, Romania.ORCID 0000-0002-9500-4498
Roxana-Elena Goroftei-BogdanMedical Clinic Department, Dunarea de Jos University, 800008 Galati, Romania.
Cristian GutuMedical Clinic Department, Dunarea de Jos University, 800008 Galati, Romania.ORCID 0009-0000-5081-3577
Manuela ArbuneMedical Clinic Department, Dunarea de Jos University, 800008 Galati, Romania.ORCID 0000-0002-4762-0755

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clinical manifestations and mortality caused by SARS-CoV-2 change, consistent with circulating viral variants and population immunity. Our retrospective study analyses the hospitalised COVID-19 cases from Romania in 2024 comparative with 2020. The circulation of SARS-CoV-2 in the fourth year of the pandemic led to changes in the characteristics of the hospitalised population, including clinical, biological, and radiological profiles, as well as an increase in 90-day mortality after hospitalisation. The hospitalised population became predominantly older with multiple comorbidities. Notable changes in symptomatology included an increase in the frequency of rhinorrhoea and syncope, while disturbances in taste and smell were less frequent. The mortality rate within the first 90 days increased in 2024 to 9%. Older age and a higher index of chronic comorbidities were associated with a higher frequency of severe forms and deaths within 90 days post-COVID-19. Hospitalisation for COVID-19 may be an unfavourable prognostic factor for the elderly population.

Indexed as

COVID-19HospitalizationAdultAgedAged, 80 and overComorbidityFemaleHumansMaleMiddle AgedRetrospective StudiesRomaniaSARS-CoV-290-day mortalityclinical variationsCOVID-19pneumoniaprognosis

Identifiers

PMID40431642
PMCPMC12115830

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.