Evidence map›Paper›PMID 40431638›Full record

ArticleViruses2025

The Impact of

Chaitra A Takle, Eun-Jin Choi, Eun Seok Choi, Devang Deepak, Kashish Khatkar, Jong Min Choi, Ke Zhang, Sung Yun Jung, Tian Wang, Wenzhe Wu and 1 more

Abstract read
In one paragraph

Article in Viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Chaitra A TakleDepartment of Pediatrics, University of Texas Medical Branch, Galveston, TX 77555, USA.
Eun-Jin ChoiDepartment of Pediatrics, University of Texas Medical Branch, Galveston, TX 77555, USA.ORCID 0000-0003-3812-4677
Eun Seok ChoiDepartment of Pediatrics, University of Texas Medical Branch, Galveston, TX 77555, USA.ORCID 0000-0001-6073-248X
Devang DeepakDepartment of Pediatrics, University of Texas Medical Branch, Galveston, TX 77555, USA.ORCID 0009-0009-1635-2944
Kashish KhatkarDepartment of Pediatrics, University of Texas Medical Branch, Galveston, TX 77555, USA.
Jong Min ChoiLester and Sue Smith Breast Center, Baylor College of Medicine, Houston, TX 77030, USA.ORCID 0000-0002-5282-7697
Ke ZhangDepartment of Pediatrics, University of Texas Medical Branch, Galveston, TX 77555, USA.
Sung Yun JungVerna and Marrs McLean Department of Biochemistry and Molecular Pharmacology, Baylor College of Medicine, Houston, TX 77030, USA.ORCID 0000-0003-1521-7977
Tian WangDepartment of Microbiology and Immunology, University of Texas Medical Branch, Galveston, TX 77555, USA.
Wenzhe WuDepartment of Pediatrics, University of Texas Medical Branch, Galveston, TX 77555, USA.ORCID 0000-0002-8030-3698
Xiaoyong BaoDepartment of Pediatrics, University of Texas Medical Branch, Galveston, TX 77555, USA.ORCID 0000-0002-6884-2584

Funding

Infectious Diseases and Inflammatory Disorders Training ProgramT35AI078878 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI WANG, TIAN · 2008 to 2025
$701k
tRNA-derived RNA Fragments and their Role in Nasal SARS-CoV-2 InfectionR21AI166543 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI BAO, XIAOYONG · 2022 to 2023
$680k
ALA ERP-1252718NIAID NIH HHS R21 AI166543NIAID NIH HHS T35 AI078878NIH HHS R21 AI166543,T35AI0778878
6 · The paper itself

Abstract

Respiratory syncytial virus (RSV) is a leading cause of lower respiratory tract infections in infants, young children, and immunocompromised individuals. Currently, FDA-approved monoclonal antibody therapies are limited to infants and young children with severe RSV disease. As a result, there is an urgent need for comprehensive studies of RSV pathogenesis to support the development of new therapeutic strategies. Exchange proteins directly activated by cAMP (

Indexed as

Guanine Nucleotide Exchange FactorsRespiratory Syncytial Virus, HumanRespiratory Syncytial Virus InfectionsCell LineHost-Pathogen InteractionsHumansVirus ReplicationGuanine Nucleotide Exchange FactorsRAPGEF4 protein, humanEPAC2JUPRSVviral gene transcription and viral genome replication

Identifiers

PMID40431638
PMCPMC12115799

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.