Evidence map›Paper›PMID 40431586›Full record

ArticleVeterinary sciences2025

Circulating ACTH and Cortisol Investigations in Standardbred Racehorses Under Training and Racing Sessions.

Cristina Cravana, Pietro Medica, Esterina Fazio, Katiuska Satué, Giacoma Brancato, Deborah La Fauci, Giuseppe Bruschetta

Abstract read
In one paragraph

Article in Veterinary sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Cristina CravanaUnit of Veterinary Physiology, Department of Veterinary Sciences, Messina University, Polo Universitario Annunziata, 98168 Messina, Italy.ORCID 0000-0001-5072-4806
Pietro MedicaUnit of Veterinary Physiology, Department of Veterinary Sciences, Messina University, Polo Universitario Annunziata, 98168 Messina, Italy.ORCID 0000-0001-9291-6101
Esterina FazioUnit of Veterinary Physiology, Department of Veterinary Sciences, Messina University, Polo Universitario Annunziata, 98168 Messina, Italy.ORCID 0000-0002-6377-0737
Katiuska SatuéDepartment of Animal Medicine and Surgery, Faculty of Veterinary, Cardenal Herrera-CEU University, Alfara del Patriarca, 46115 Valencia, Spain.ORCID 0000-0002-3168-0104
Giacoma BrancatoUnit of Veterinary Physiology, Department of Veterinary Sciences, Messina University, Polo Universitario Annunziata, 98168 Messina, Italy.ORCID 0009-0005-9045-3090
Deborah La FauciUnit of Veterinary Physiology, Department of Veterinary Sciences, Messina University, Polo Universitario Annunziata, 98168 Messina, Italy.ORCID 0000-0003-3753-771X
Giuseppe BruschettaUnit of Veterinary Physiology, Department of Veterinary Sciences, Messina University, Polo Universitario Annunziata, 98168 Messina, Italy.ORCID 0000-0002-9065-4467

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The hypothalamic-pituitary-adrenal (HPA) axis is a neuroendocrine system involved in the coping response to stressful challenges during exercise stimuli. Exercise represents a significant disruptor of homeostasis, inducing an ACTH-cortisol co-secretion, based on different characteristics of exercise in sport horses. Based on this statement, the aim of this study is to evaluate the circulating adrenocorticotropin and cortisol changes in Standardbred trotters, after training and racing sessions, considering the different age and sex. In particular, the aim is to determine to what extent the level of ACTH and cortisol increases during maximum effort in competition conditions (racing), and to compare two exercise conditions of different intensity, training and racing sessions, and effects on ACTH and cortisol responses. Ten Standardbreds, three females and seven males, clinically healthy, were enrolled and subjected to two exercise conditions: a non-competitive session (training) and then a competitive event (racing). Four of them were 2-year-olds and a further six were 3-year-olds. Training and racing effects on both ACTH (

Indexed as

ACTHcortisolracingStandardbredtraining

Identifiers

PMID40431586
PMCPMC12116121

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.