Evidence map›Paper›PMID 40431567›Full record

ArticleVeterinary sciences2025

Clinical Approach to Cleft Lip and Palate with or Without Surgical Correction in Ten Brachycephalic Puppies.

Gleice Mendes Xavier, Keylla Helena Nobre Pacífico Pereira, Kárita da Mata Fuchs, Júlia Conseza Mendonça, Rebeca Bastos Abibe, Claudia Valéria Seullner Brandão, Maricy Apparício, Fabiana Ferreira de Souza, Matheus Gabriel Crema, Vânia Maria de Vasconcelos Machado and 1 more

Abstract readCase Reports
In one paragraph

Article in Veterinary sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Gleice Mendes XavierDepartment of Veterinary Clinic, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu 18618-681, Brazil.ORCID 0000-0002-5983-0602
Keylla Helena Nobre Pacífico PereiraDepartment of Veterinary Clinic, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu 18618-681, Brazil.ORCID 0000-0001-6474-4808
Kárita da Mata FuchsDepartment of Veterinary Clinic, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu 18618-681, Brazil.
Júlia Conseza MendonçaDepartment of Veterinary Clinic, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu 18618-681, Brazil.
Rebeca Bastos AbibeDepartment of Veterinary Surgery and Animal Reproduction, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu 18618-681, Brazil.ORCID 0000-0002-5542-5554
Claudia Valéria Seullner BrandãoDepartment of Veterinary Surgery and Animal Reproduction, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu 18618-681, Brazil.ORCID 0000-0002-2011-5214
Maricy ApparícioDepartment of Veterinary Surgery and Animal Reproduction, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu 18618-681, Brazil.ORCID 0000-0001-8360-0471
Fabiana Ferreira de SouzaDepartment of Veterinary Surgery and Animal Reproduction, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu 18618-681, Brazil.ORCID 0000-0003-4721-1801
Matheus Gabriel CremaDepartment of Veterinary Surgery and Animal Reproduction, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu 18618-681, Brazil.
Vânia Maria de Vasconcelos MachadoDepartment of Veterinary Surgery and Animal Reproduction, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu 18618-681, Brazil.ORCID 0000-0002-9057-5793
Maria Lucia Gomes LourençoDepartment of Veterinary Clinic, School of Veterinary Medicine and Animal Science, São Paulo State University (UNESP), Botucatu 18618-681, Brazil.ORCID 0000-0002-8337-4168

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Congenital defects are among the leading causes of neonatal mortality in small animals. Among them, cleft palate is one of the most commonly found malformations in dogs. Appropriate clinical management and surgical correction are determining factors for the survival of puppies affected by this alteration. Thus, the objective of this study is to describe 10 clinical cases of successful clinical management of cleft palate, highlighting the therapeutic strategies used, the results obtained, and the evolution of patients after treatment. Ten neonatal dogs of three breeds were treated by the Small Animal Reproduction Service of FMVZ, Unesp-Botucatu: French Bulldog (6), Pug (3), and American Bully (1) presented with cleft palate at birth or during the first week of age. Patients underwent clinical and nutritional management, in addition to immunological support. At four months of age, the patients underwent medially positioned flap repair. The animals were fed via an esophageal tube for 10 days after surgery. The clinical management proved to be effective since, throughout the follow-up, the animals showed good development and did not present complications arising from the cleft palate, and the surgical procedures were successful, restoring the quality of life of the animals.

Indexed as

caninecongenital anomalyneonatespalatoschisissurgical palate repair

Identifiers

PMID40431567
PMCPMC12116112

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.