Evidence map›Paper›PMID 40431523›Full record

ArticleVeterinary sciences2025

Behavioral Changes in Cats Following Deslorelin Implantation or Surgical Gonadectomy.

Mihaela Velkovska, Maria Pereira, Maja Zakošek Pipan, Darja Pavlin, Lluis Ferré-Dolcet, Simona Normando, Stefano Romagnoli

Abstract read
In one paragraph

Article in Veterinary sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mihaela VelkovskaClinic for Reproduction and Large Animals, Veterinary Faculty, University of Ljubljana, 1000 Ljubljana, Slovenia.
Maria PereiraDepartment of Animal Medicine, Production and Health, University of Padova, 35020 Legnaro, Padova, Italy.ORCID 0009-0001-1394-0638
Maja Zakošek PipanClinic for Reproduction and Large Animals, Veterinary Faculty, University of Ljubljana, 1000 Ljubljana, Slovenia.ORCID 0000-0003-4035-9408
Darja PavlinClinic for Small Animals, Veterinary Faculty, University of Ljubljana, 1000 Ljubljana, Slovenia.
Lluis Ferré-DolcetAnicura Ars Veterinaria, 08034 Barcelona, Spain.ORCID 0000-0002-4994-768X
Simona NormandoDepartment of Comparative Biomedicine and Food Science, University of Padova, 35020 Legnaro, Padova, Italy.ORCID 0000-0002-3978-1487
Stefano RomagnoliDepartment of Animal Medicine, Production and Health, University of Padova, 35020 Legnaro, Padova, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Few studies address behavioral changes after deslorelin treatment in cats. As increasingly more owners opt for pharmacological sterilization, understanding deslorelin effects on behavior is critical. This multicentric study compared behavioral changes in cats that were surgically sterilized with those that were treated with deslorelin using an anonymous survey of 19 behavioral changes. Owners of deslorelin-implanted cats completed two questionnaires related to the flare-up and downregulation periods, while owners of gonadectomized cats completed only one questionnaire. A total of 66 answers were collected (24 for surgical sterilization, 24 for flare-up, and 18 for downregulation). Decrease in urine marking, excessive vocalization, intact male cat urine odor, and disobedience were significantly higher in downregulated cats compared to gonadectomized ones. In the flare-up group, 68% of females exhibited behavioral manifestation of induced heat. Males displayed flare-up behaviors less frequently and intensively than females after implantation with deslorelin. Age at sterilization exerted a significant effect on five behaviors in deslorelin-implanted cats. Owners of deslorelin treated cats in the downregulation phase reported a more pronounced decrease in undesirable behaviors than the owners of surgically sterilized cats.

Indexed as

castrationfelinesflare-uppharmacological sterilization

Identifiers

PMID40431523
PMCPMC12115999

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.