Evidence map›Paper›PMID 40431421›Full record

ArticleNutrients2025

3,3'-Diindolylmethane Ameliorates Metabolism Dysfunction-Associated Fatty Liver Disease via AhR/p38 MAPK Signaling.

Jiewen Su, Heng Fang, Yunfeng Lin, Yilu Yao, Yanxi Liu, Yuquan Zhong, Xudong Li, Siyu Sun, Bing Huang, Guangyu Yang and 7 more

Abstract read
In one paragraph

Article in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Jiewen SuSchool of Public Health, Sun Yat-Sen University, Guangzhou 510275, China.ORCID 0009-0004-0875-9860
Heng FangSchool of Public Health, Sun Yat-Sen University, Guangzhou 510275, China.
Yunfeng LinSchool of Public Health, Guangdong Pharmaceutical University, Guangzhou 510006, China.
Yilu YaoSchool of Basic Medicine and Public Health, Jinan University, Guangzhou 510632, China.
Yanxi LiuSchool of Public Health, Guangzhou Medical University, Guangzhou 511436, China.
Yuquan ZhongSchool of Public Health, Guangzhou Medical University, Guangzhou 511436, China.
Xudong LiDepartment of Scientific Research, Guangzhou Center for Disease Control and Prevention (Guangzhou Health Supervision Institute), Guangzhou 510405, China.ORCID 0000-0003-2392-1227
Siyu SunSchool of Public Health, Southern Medical University, Guangzhou 510515, China.
Bing HuangDepartment of Scientific Research, Guangzhou Center for Disease Control and Prevention (Guangzhou Health Supervision Institute), Guangzhou 510405, China.
Guangyu YangDepartment of Scientific Research, Guangzhou Center for Disease Control and Prevention (Guangzhou Health Supervision Institute), Guangzhou 510405, China.
Wenxue LiDepartment of Scientific Research, Guangzhou Center for Disease Control and Prevention (Guangzhou Health Supervision Institute), Guangzhou 510405, China.
Yan ZhangDepartment of Scientific Research, Guangzhou Center for Disease Control and Prevention (Guangzhou Health Supervision Institute), Guangzhou 510405, China.
Juntao LiDepartment of Scientific Research, Guangzhou Center for Disease Control and Prevention (Guangzhou Health Supervision Institute), Guangzhou 510405, China.
Jinyin WuDepartment of Scientific Research, Guangzhou Center for Disease Control and Prevention (Guangzhou Health Supervision Institute), Guangzhou 510405, China.
Weiwen LiuDepartment of Scientific Research, Guangzhou Center for Disease Control and Prevention (Guangzhou Health Supervision Institute), Guangzhou 510405, China.
Qiansheng HuSchool of Public Health, Sun Yat-Sen University, Guangzhou 510275, China.ORCID 0000-0001-6527-6436
Wei ZhuSchool of Public Health, Sun Yat-Sen University, Guangzhou 510275, China.ORCID 0000-0001-5796-4167

Funding

The Basic Research Project of Guangzhou Key Laboratory No.2024A02100001
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Basic Helix-Loop-Helix ProteinsIndolesNon-alcoholic Fatty Liver Diseasep38 Mitogen-Activated Protein KinasesReceptors, Aryl HydrocarbonAnimalsDiet, High-FatHep G2 CellsHumansLipid MetabolismLiverMaleMiceMice, Inbred C57BLSignal Transduction3,3'-diindolylmethaneAhr protein, mouseBasic Helix-Loop-Helix ProteinsIndolesp38 Mitogen-Activated Protein KinasesReceptors, Aryl Hydrocarbon3,3′-Diindolylmethanearyl hydrocarbon receptorCD36MAFLDp38 MAPK

Identifiers

PMID40431421
PMCPMC12113855

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.