Evidence map›Paper›PMID 40431410›Full record

ArticleNutrients2025

Qi Yao, Wenbo Zhang, Yuze Wang, Le Shi, Yixiao Zhao, Jiarui Liang, Yu Zhao, Jiawei Kang, Xudong Zheng, Rui Guo and 3 more

Abstract read
In one paragraph

Article in Nutrients, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Toxics · 2026
    Article
  4. Review
  5. Review
  6. Review
  7. The interplay between probiotics and mast cells in gut inflammation: a mini-review.Frontiers in cellular and infection microbiology · 2026
    Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Qi YaoLaboratory of Functional Chemistry and Nutrition of Food, College of Food Science and Engineering, Northwest A&F University, Xianyang 712100, China.
Wenbo ZhangLaboratory of Functional Chemistry and Nutrition of Food, College of Food Science and Engineering, Northwest A&F University, Xianyang 712100, China.ORCID 0000-0002-8875-5170
Yuze WangLaboratory of Functional Chemistry and Nutrition of Food, College of Food Science and Engineering, Northwest A&F University, Xianyang 712100, China.
Le ShiLaboratory of Functional Chemistry and Nutrition of Food, College of Food Science and Engineering, Northwest A&F University, Xianyang 712100, China.
Yixiao ZhaoLaboratory of Functional Chemistry and Nutrition of Food, College of Food Science and Engineering, Northwest A&F University, Xianyang 712100, China.ORCID 0009-0003-9832-4395
Jiarui LiangLaboratory of Functional Chemistry and Nutrition of Food, College of Food Science and Engineering, Northwest A&F University, Xianyang 712100, China.
Yu ZhaoLaboratory of Functional Chemistry and Nutrition of Food, College of Food Science and Engineering, Northwest A&F University, Xianyang 712100, China.
Jiawei KangLaboratory of Functional Chemistry and Nutrition of Food, College of Food Science and Engineering, Northwest A&F University, Xianyang 712100, China.
Xudong ZhengLaboratory of Functional Chemistry and Nutrition of Food, College of Food Science and Engineering, Northwest A&F University, Xianyang 712100, China.
Rui GuoLaboratory of Functional Chemistry and Nutrition of Food, College of Food Science and Engineering, Northwest A&F University, Xianyang 712100, China.
Tian YuanShaanxi Key Laboratory of Natural Products & Chemical Biology, College of Chemistry & Pharmacy, Northwest A&F University, Xianyang 712100, China.
Yongbo SheLaboratory of Functional Chemistry and Nutrition of Food, College of Food Science and Engineering, Northwest A&F University, Xianyang 712100, China.
Zhigang LiuLaboratory of Functional Chemistry and Nutrition of Food, College of Food Science and Engineering, Northwest A&F University, Xianyang 712100, China.ORCID 0000-0002-6863-6561

Funding

Guangdong Basic and Applied Basic Research Foundation 2021A1515110813Guangdong Regional Consolidated Fund-Youth Fund Project 2022A1515110717Shenzhen Fundamental Research Program JYC20220530161401004the China Postdoctoral Science Foundation 2022M72261the National Natural Science Foundation of China 82103842
6 · The paper itself

Abstract

backgroundIrritable bowel syndrome (IBS) significantly impairs the lifestyle and quality of life of the global population. However, the underlying pathophysiological mechanisms remain largely elusive. While conventional pharmacological approaches show limited therapeutic efficacy, emerging microbiota-targeted dietary interventions present promising alternatives.

objectivesThe present study aimed to elucidate the molecular mechanisms by which a synbiotic mitigates IBS and associated colonic dysfunctions in C57BL/6 mice.

methodsThe mouse model was induced by a

resultsThe 32-day synbiotic intervention, consisting of

conclusionsIn conclusion, the synbiotic composed of

Indexed as

GalactoseGastrointestinal MicrobiomeIrritable Bowel SyndromeLactiplantibacillus plantarumMast CellsOligosaccharidesSynbioticsAnimalsColonDisease Models, AnimalMaleMiceMice, Inbred C57BLGalactoseOligosaccharidesgut microbiotaIBSinflammationmast cellssynbiotic

Identifiers

PMID40431410
PMCPMC12113827

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.