Evidence map›Paper›PMID 40431319›Full record

ReviewMicroorganisms2025

Eugenol Nanoparticles in Dental Composites: Literature Review of Antimicrobial, Anti-Inflammatory, and Clinical Applications.

Fatima Zahra Kamal, Alin Ciobica, Gabriel Dascalescu, Said Rammali, Mohamed El Aalaoui, Radu Lefter, Ioana Vata, Vasile Burlui, Bogdan Novac

Abstract readReview
In one paragraph

Review in Microorganisms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Efficacy ofOpen veterinary journal · 2026
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Fatima Zahra KamalHigher Institute of Nursing Professions and Health Technical (ISPITS), Marrakech 40000, Morocco.ORCID 0000-0001-5748-8500
Alin CiobicaDepartment of Biology, Faculty of Biology, Alexandru Ioan Cuza University of Iasi, 20th Carol I Avenue, 700506 Iasi, Romania.ORCID 0000-0002-1750-6011
Gabriel DascalescuDepartment of Biology, Faculty of Biology, Alexandru Ioan Cuza University of Iasi, 20th Carol I Avenue, 700506 Iasi, Romania.ORCID 0009-0001-1962-7861
Said RammaliLaboratory of Agro-Alimentary and Health, Faculty of Sciences and Techniques, Hassan First University of Settat, BP 539, Settat 26000, Morocco.ORCID 0009-0007-5546-5453
Mohamed El AalaouiNational Institute of Agricultural Research, Avenue Ennasr, BP 415 Rabat Principal, Rabat 10090, Morocco.
Radu LefterCenter of Biomedical Research, Romanian Academy, 700506 Iasi, Romania.ORCID 0000-0003-2941-738X
Ioana VataClinical Department, Apollonia University, Păcurari Street 11, 700511 Iasi, Romania.
Vasile BurluiClinical Department, Apollonia University, Păcurari Street 11, 700511 Iasi, Romania.ORCID 0009-0001-2699-9321
Bogdan NovacFaculty of Medicine, "Grigore T. Popa" University of Medicine and Pharmacy of Iasi, 16th Universitatii Street, 700115 Iasi, Romania.ORCID 0000-0003-4501-1718

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The formation of microbial colonies and biofilms are common on dental restorations. This can lead to secondary caries. Another common complication is the post-operative inflammation noted in patients. The traditionally used dental composites are designed without the inherent components having antimicrobial and inflammatory properties. This has become a major challenge in current restorative dentistry applications. In order to address these challenges, a possible approach is to incorporate eugenol nanoparticles (NPs) into dental composites. This approach can offer dual therapeutic benefits since eugenol possess both antimicrobial and inflammatory properties. In fact, compared to synthetic antimicrobial agents, eugenol exhibits antibacterial activity not only against

Indexed as

antibacterialanti-inflammatorybiofilmcontrol releaseeugenolrestorative dentistry

Identifiers

PMID40431319
PMCPMC12114176

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.