Evidence map›Paper›PMID 40431317›Full record

ArticleMicroorganisms2025

In Silico Design, Optimization, and Evaluation of a Multi-Epitope Vaccine Targeting the

Dhiraj Chundru, Shailes Bhattrai, Madhusudan Timilsina, Hyun Lillehoj, Zhifeng Sun, Mostafa Ghanem, Charles Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microorganisms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Frontiers in immunology · 2026
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Dhiraj ChundruDepartment of Veterinary Medicine, Virginia-Maryland College of Veterinary Medicine, Maryland Campus, College Park, MD 20740, USA.ORCID 0009-0008-3085-381X
Shailes BhattraiAnimal Biosciences and Biotechnology Laboratory, Beltsville Agricultural Research Center, Agricultural Research Service-US Department of Agriculture, Beltsville, MD 20705, USA.
Madhusudan TimilsinaDepartment of Veterinary Medicine, Virginia-Maryland College of Veterinary Medicine, Maryland Campus, College Park, MD 20740, USA.ORCID 0009-0005-7824-3816
Hyun LillehojAnimal Biosciences and Biotechnology Laboratory, Beltsville Agricultural Research Center, Agricultural Research Service-US Department of Agriculture, Beltsville, MD 20705, USA.ORCID 0000-0001-7755-6216
Zhifeng SunAnimal Biosciences and Biotechnology Laboratory, Beltsville Agricultural Research Center, Agricultural Research Service-US Department of Agriculture, Beltsville, MD 20705, USA.
Mostafa GhanemDepartment of Veterinary Medicine, Virginia-Maryland College of Veterinary Medicine, Maryland Campus, College Park, MD 20740, USA.ORCID 0000-0001-9647-1357
Charles LiAnimal Biosciences and Biotechnology Laboratory, Beltsville Agricultural Research Center, Agricultural Research Service-US Department of Agriculture, Beltsville, MD 20705, USA.

Funding

ARS/USDA CRIS Project 8042- 32000-115-00D
6 · The paper itself

Abstract

Necrotic enteritis (NE), caused by pathogenic

Indexed as

B-cellsCD4+ T cellCD8+ CTLClostridium perfringenscollagen adhesin protein (CNA)epitopesimmunoinformaticsmulti-epitope vaccine (MEV)necrotic enteritis

Identifiers

PMID40431317
PMCPMC12113974

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.