Evidence map›Paper›PMID 40431277›Full record

ReviewMicroorganisms2025

Remarks on Life Feasibility on the Red Planet.

Fiorella Mancini, Giuseppe Graziano

Abstract readReview
In one paragraph

Review in Microorganisms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Fiorella ManciniDipartimento di Scienze e Tecnologie, Università del Sannio, Via Francesco de Sanctis snc, 82100 Benevento, Italy.ORCID 0009-0007-5503-3714
Giuseppe GrazianoDipartimento di Scienze e Tecnologie, Università del Sannio, Via Francesco de Sanctis snc, 82100 Benevento, Italy.ORCID 0000-0001-6935-8172

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The current strong interest in the exploration of Mars leads to the question of the actual possibility of the presence or possible past or future development of life on the planet. Several clues suggest that liquid water could be stably present under the surface of Mars, but on the condition that it is rich in perchlorate salts, abundant in the Martian soil, which would allow for water to remain liquid at the very low temperatures found on the planet. In this work, the main evidence on the permissiveness of Martian environments to microbial life is reviewed, with particular attention to the evaluation of the tolerance limit to the perchlorates of different microorganisms. Furthermore, a reasonable theoretical approach is offered to calculate the stability of globular proteins in aqueous solutions rich in perchlorates, trying to provide, given the current lack of valid experimental data, a rational means to try to understand the behaviour of proteins in environmental conditions very far from those of Earth.

Indexed as

lifeliquid waterMarsperchloratesperchlorate toleranceprotein stabilitysalty brines

Identifiers

PMID40431277
PMCPMC12114179

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.