Evidence map›Paper›PMID 40431261›Full record

ArticleMicroorganisms2025

Impact of SARS-CoV-2 P.1 Variant Infection on the Nasopharyngeal Commensal Bacterial Microbiome of Individuals from the Brazilian Amazon.

Amanda Mendes Silva Cruz, Jedson Ferreira Cardoso, Kenny Costa Pinheiro, Jessylene Almeida Ferreira, Luana Soares Barbagelata, Sandro Patroca Silva, Wanderley Dias Chagas Junior, Patrícia Santos Lobo, Dielle Monteiro Teixeira, Walter André Junior and 5 more

Abstract read
In one paragraph

Article in Microorganisms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Amanda Mendes Silva CruzVirology Section, Evandro Chagas Institute, Secretariat for Health and Environmental Surveillance, Ministry of Health, Highway BR 316-KM 07, S/N, Levilândia, Ananindeua 67030-000, PA, Brazil.
Jedson Ferreira CardosoVirology Section, Evandro Chagas Institute, Secretariat for Health and Environmental Surveillance, Ministry of Health, Highway BR 316-KM 07, S/N, Levilândia, Ananindeua 67030-000, PA, Brazil.ORCID 0000-0002-3680-6327
Kenny Costa PinheiroVirology Section, Evandro Chagas Institute, Secretariat for Health and Environmental Surveillance, Ministry of Health, Highway BR 316-KM 07, S/N, Levilândia, Ananindeua 67030-000, PA, Brazil.ORCID 0000-0003-3452-9271
Jessylene Almeida FerreiraVirology Section, Evandro Chagas Institute, Secretariat for Health and Environmental Surveillance, Ministry of Health, Highway BR 316-KM 07, S/N, Levilândia, Ananindeua 67030-000, PA, Brazil.
Luana Soares BarbagelataVirology Section, Evandro Chagas Institute, Secretariat for Health and Environmental Surveillance, Ministry of Health, Highway BR 316-KM 07, S/N, Levilândia, Ananindeua 67030-000, PA, Brazil.
Sandro Patroca SilvaArbovirology Section, Evandro Chagas Institute, Secretariat for Health and Environmental Surveillance, Ministry of Health, Highway BR 316-KM 07, S/N, Levilândia, Ananindeua 67030-000, PA, Brazil.ORCID 0000-0001-7185-4538
Wanderley Dias Chagas JuniorVirology Section, Evandro Chagas Institute, Secretariat for Health and Environmental Surveillance, Ministry of Health, Highway BR 316-KM 07, S/N, Levilândia, Ananindeua 67030-000, PA, Brazil.
Patrícia Santos LoboVirology Section, Evandro Chagas Institute, Secretariat for Health and Environmental Surveillance, Ministry of Health, Highway BR 316-KM 07, S/N, Levilândia, Ananindeua 67030-000, PA, Brazil.ORCID 0000-0003-0209-6969
Dielle Monteiro TeixeiraVirology Section, Evandro Chagas Institute, Secretariat for Health and Environmental Surveillance, Ministry of Health, Highway BR 316-KM 07, S/N, Levilândia, Ananindeua 67030-000, PA, Brazil.
Walter André JuniorMinistry of Health, Central Public Health Laboratory of Amazonas, R. Emílio Moreira, 528-Centro, Manaus 69020-040, AM, Brazil.
Inaiah Ordenes SilvaMinistry of Health, Amazonas Health Surveillance Foundation-Dr. Rosemary Costa, Torquato Tapajós Avenue, 4010-Santo Antônio College, Manaus 69093-018, AM, Brazil.
Mirleide Cordeiro SantosVirology Section, Evandro Chagas Institute, Secretariat for Health and Environmental Surveillance, Ministry of Health, Highway BR 316-KM 07, S/N, Levilândia, Ananindeua 67030-000, PA, Brazil.
Luana Silva Soares FariasVirology Section, Evandro Chagas Institute, Secretariat for Health and Environmental Surveillance, Ministry of Health, Highway BR 316-KM 07, S/N, Levilândia, Ananindeua 67030-000, PA, Brazil.ORCID 0000-0001-9509-4019
Maisa Silva SousaCenter for Tropical Medicine, Federal University of Pará, Av. Generalíssimo Deodoro, 92, Umarizal, Belém 66055-240, PA, Brazil.ORCID 0000-0001-9944-7838
Fernando Neto TavaresVirology Section, Evandro Chagas Institute, Secretariat for Health and Environmental Surveillance, Ministry of Health, Highway BR 316-KM 07, S/N, Levilândia, Ananindeua 67030-000, PA, Brazil.ORCID 0000-0002-1385-5169

Funding

CDC HHS NU2GGH002174Fundação Oswaldo Cruz NU2GGH002174National Council for Scientific and Technological Development 159996/2021-0Public Ministry of Labor through the Research Support and Development Foudation 4648 MPT/IEC/FADESP
6 · The paper itself

Abstract

It is important to understand which bacterial taxa are most abundant during SARS-CoV-2 infection and to promote mitigation strategies for conditions subsequent to infection. Nasopharyngeal swab samples were collected from patients infected with SARS-CoV-2 and their family contacts (uninfected and asymptomatic) during the outbreak of the P.1 variant of SARS-CoV-2 in Parintins, Amazonas-Brazil, in March 2021. The samples were investigated by a shotgun sequencing metagenomic approach using the NextSeq 500 Illumina® system. The samples were stratified according to the presence or absence of SARS-CoV-2, household group, sex, and age. Of the total of 63 individuals, 37 (58.73%) were positive for SARS-CoV-2 and 26 (41.27%) were negative for SARS-CoV-2 and other respiratory viruses (FLU, AdV, HBoV, HCoV, HMPV, RSV, PIV, HRV). The alpha diversity indexes Chao1, species observed, Simpson, and Inv Simpson demonstrated a significant difference (

Indexed as

alpha diversitybeta diversityBrazilian AmazonmetagenomicnasopharyngealP.1 variantSARS-CoV-2

Identifiers

PMID40431261
PMCPMC12113811

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.