Evidence map›Paper›PMID 40430953›Full record

ArticlePharmaceutics2025

Feasibility of Hot Melt Extrusion in Converting Water-Based Nanosuspensions into Solid Dosage Forms.

Erasmo Ragucci, Marco Uboldi, Adam Sobczuk, Giorgio Facchetti, Alice Melocchi, Mauro Serratoni, Lucia Zema

Abstract read
In one paragraph

Article in Pharmaceutics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Erasmo RagucciPhormulaMi Research Group, Sezione di Tecnologia e Legislazione Farmaceutiche "Maria Edvige Sangalli", Dipartimento di Scienze Farmaceutiche, Università degli Studi di Milano, Via Giuseppe Colombo 71, 20133 Milano, Italy.
Marco UboldiPhormulaMi Research Group, Sezione di Tecnologia e Legislazione Farmaceutiche "Maria Edvige Sangalli", Dipartimento di Scienze Farmaceutiche, Università degli Studi di Milano, Via Giuseppe Colombo 71, 20133 Milano, Italy.ORCID 0000-0003-0179-2233
Adam SobczukNovartis Pharma AG, 4056 Basel, Switzerland.
Giorgio FacchettiDipartimento di Scienze Farmaceutiche, Università degli Studi di Milano, Via Venezian 21, 20133 Milano, Italy.ORCID 0000-0002-1260-1335
Alice MelocchiPhormulaMi Research Group, Sezione di Tecnologia e Legislazione Farmaceutiche "Maria Edvige Sangalli", Dipartimento di Scienze Farmaceutiche, Università degli Studi di Milano, Via Giuseppe Colombo 71, 20133 Milano, Italy.ORCID 0000-0001-5602-3314
Mauro SerratoniNovartis Pharma AG, 4056 Basel, Switzerland.ORCID 0009-0009-5049-0750
Lucia ZemaPhormulaMi Research Group, Sezione di Tecnologia e Legislazione Farmaceutiche "Maria Edvige Sangalli", Dipartimento di Scienze Farmaceutiche, Università degli Studi di Milano, Via Giuseppe Colombo 71, 20133 Milano, Italy.ORCID 0000-0001-8405-226X

Funding

University of Milan not available
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

granuleshot melt extrusionimmediate releasemodified releasenanosuspension

Identifiers

PMID40430953
PMCPMC12115045

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.