ArticlePathogens (Basel, Switzerland)2025
Human Papillomavirus Positivity and Cognitive Function in Older U.S. Adults: A Cross-Sectional Population-Based Study.
Article in Pathogens (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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7 authors.
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Abstract
Prior research has reported an association between human papillomavirus (HPV) seropositivity and dementia or Alzheimer's disease. This study aimed to cross-sectionally investigate the association between HPV seropositivity and cognitive function in older adults. The data used for this study were from the 2011-2014 National Health and Nutrition Examination Survey (NHANES) cycles. To account for the complex survey design and missing data, we applied survey-weighted regression models to each imputed dataset, using multiple imputation techniques. Across all cognitive test outcomes, no statistically significant association was observed between HPV status and cognitive performance after controlling for covariates. These findings suggest that there may not be a significant association between HPV infection and cognitive scores in this NHANES sample. Stakeholders, including policymakers and healthcare providers, should consider these findings in their professional decision-making. Future research should investigate the association between HPV seropositivity and cognition using other samples in order to further characterize the association between HPV and cognitive function in older adults.
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