Evidence map›Paper›PMID 40430807›Full record

ArticlePathogens (Basel, Switzerland)2025

Genetic and Antigenic Diversity of

Trieu Phi Long, Vo Viet Cuong, Bui Thi Lan Anh, Trinh Van Toan, Vu Thi Loan, Pham Viet Hung, Le Thi Lan Anh, Nguyen Ngoc Tan, Luong Thi Mo, Le Van Khanh and 1 more

Abstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Trieu Phi LongGraduate University of Science and Technology, Vietnam Academy of Science and Technology, Hanoi 100000, Vietnam.
Vo Viet CuongInstitute of Tropical Medicine, Joint Vietnam-Russia Tropical Science and Technology Research Center, Hanoi 100000, Vietnam.ORCID 0000-0001-5147-7085
Bui Thi Lan AnhInstitute of Tropical Medicine, Joint Vietnam-Russia Tropical Science and Technology Research Center, Hanoi 100000, Vietnam.ORCID 0000-0001-9266-2156
Trinh Van ToanInstitute of Tropical Medicine, Joint Vietnam-Russia Tropical Science and Technology Research Center, Hanoi 100000, Vietnam.
Vu Thi LoanInstitute of Tropical Medicine, Joint Vietnam-Russia Tropical Science and Technology Research Center, Hanoi 100000, Vietnam.
Pham Viet HungInstitute of Tropical Medicine, Joint Vietnam-Russia Tropical Science and Technology Research Center, Hanoi 100000, Vietnam.
Le Thi Lan AnhInstitute of Tropical Medicine, Joint Vietnam-Russia Tropical Science and Technology Research Center, Hanoi 100000, Vietnam.ORCID 0000-0002-5927-9857
Nguyen Ngoc TanInstitute of Tropical Medicine, Joint Vietnam-Russia Tropical Science and Technology Research Center, Hanoi 100000, Vietnam.
Luong Thi MoSouthern Branch of the Joint Vietnam-Russia Tropical Science and Technology Research Center, Ho Chi Minh City 700000, Vietnam.ORCID 0000-0002-6035-5933
Le Van KhanhInstitute of Biomedicine and Pharmacy, Vietnam Military Medical University, Hanoi 100000, Vietnam.
Hoang Van TongInstitute of Biomedicine and Pharmacy, Vietnam Military Medical University, Hanoi 100000, Vietnam.ORCID 0000-0002-7170-8810

Funding

Vietnam Ministry of Science and Technology NVQG-2019/ĐT.02
6 · The paper itself

Abstract

background

methodsGenotyping was performed on 106

resultsWe found that 84.9% of the strains carried VR3 families 36 or 35-1, with VR1, VR2, and VR3 families 22-25, 14, and 36 being the most prevalent. Among the 106 serogroup B isolates, 20 variants of the porB allele 3 were identified, with porB 3-1212 being the most frequent (30.2%). Dominant PorB variable loops included L1.6, L4.5, L5.7, L6.6, and L7.13. fHbp variant group 2 was predominant (104/106 strains), and 12 FetA allele variants were identified, with F1-7 being the most common (47.2%). Three clonal complexes were identified, and clonal complex ST-32 was the most predominant. Fifty-five strains (51.9%) belonged to sequence types that have not yet been assigned to any clonal complexes, and 15 strains (14.1%) with allelic profiles were not assigned to STs. The 3-253 and 3-1212 alleles of porB, the F1-7 variant of FetA, the ST-44 and ST-1576 sequence types, and the ST-41/44 complex were observed more frequently in patients compared to asymptomatic carriers, suggesting their association with more virulence.

conclusionsThis study showed a high genetic and antigenic diversity of

Indexed as

Antigenic VariationAntigens, BacterialGenetic VariationMeningococcal InfectionsNeisseria meningitidis, Serogroup BAdolescentFemaleGenotypeHumansMaleMeningitis, MeningococcalVietnamAntigens, Bacterialantigenic variationgenetic diversitymeningitisN. meningitidisVietnam

Identifiers

PMID40430807
PMCPMC12114657

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