Evidence map›Paper›PMID 40430806›Full record

ArticlePathogens (Basel, Switzerland)2025

Genetic Epidemiology and Resistance Investigations of Clinical Yeasts in Alexandria, Egypt.

Bram Spruijtenburg, Carolina Melchior do Prado, Mats van Kempen, Sherine M Shawky, Jacques F Meis, Vânia Aparecida Vicente, Flavio Queiroz-Telles, Theun de Groot, Mohammed A El-Kholy, Eelco F J Meijer

Abstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Bram SpruijtenburgRadboudumc-CWZ Center of Expertise for Mycology, 6532 SZ Nijmegen, The Netherlands.ORCID 0000-0002-6734-361X
Carolina Melchior do PradoRadboudumc-CWZ Center of Expertise for Mycology, 6532 SZ Nijmegen, The Netherlands.ORCID 0000-0003-0272-0709
Mats van KempenRadboudumc-CWZ Center of Expertise for Mycology, 6532 SZ Nijmegen, The Netherlands.
Sherine M ShawkyDepartment of Microbiology, Medical Research Institute, Alexandria University, Alexandria 5422021, Egypt.
Jacques F MeisRadboudumc-CWZ Center of Expertise for Mycology, 6532 SZ Nijmegen, The Netherlands.ORCID 0000-0003-3253-6080
Vânia Aparecida VicentePostgraduate Program in Microbiology, Parasitology and Pathology, Biological Sciences, Department of Basic Pathology, Federal University of Paraná, Curitiba 82590-300, Brazil.ORCID 0000-0002-2953-4861
Flavio Queiroz-TellesDepartment of Public Health, Hospital de Clínicas, Federal University of Paraná, Curitiba 80060-900, Brazil.ORCID 0000-0001-7034-2418
Theun de GrootRadboudumc-CWZ Center of Expertise for Mycology, 6532 SZ Nijmegen, The Netherlands.ORCID 0000-0001-5841-6461
Mohammed A El-KholyDepartment of Microbiology and Biotechnology, Clinical and Biological Sciences Division, College of Pharmacy, Arab Academy of Science, Technology and Maritime Transport (AASTMT), Alexandria 1029, Egypt.ORCID 0000-0002-4944-5962
Eelco F J MeijerRadboudumc-CWZ Center of Expertise for Mycology, 6532 SZ Nijmegen, The Netherlands.

Funding

Canisius-Wilhelmina Hospital CWZ_001421
6 · The paper itself

Abstract

Yeast bloodstream infections lead to high mortality and morbidity and are mostly observed in immunocompromised patients. In Africa, only a few studies have characterized clinical yeasts. To increase insight into yeast resistance and transmission in Africa, we identified various yeasts from Alexandria, Egypt and performed antifungal susceptibility testing (AFST) and genotyping. A total of 1307 single isolates from unique patients, recovered from different anatomical sites including the bloodstream, retrieved from a reference laboratory in Alexandria, Egypt were studied. All isolates were identified with MALDI-TOF MS, while some were initially identified with a Vitek 2 Compact system. Short tandem repeat (STR) genotyping was performed for the most common species, and AFST was performed with microbroth dilution. Among bloodstream isolates (

Indexed as

CandidaDrug Resistance, FungalYeastsAntifungal AgentsEgyptFemaleGenotypeHumansMaleMicrobial Sensitivity TestsMicrosatellite RepeatsMiddle AgedMolecular EpidemiologyMycological Typing TechniquesSpectrometry, Mass, Matrix-Assisted Laser Desorption-IonizationAntifungal Agentsantifungal resistanceCandidacandidemiacandidiasisepidemiologygenotypingshort tandem repeats

Identifiers

PMID40430806
PMCPMC12114656

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.