Evidence map›Paper›PMID 40430804›Full record

ArticlePathogens (Basel, Switzerland)2025

3,3'-((3-Hydroxyphenyl)azanediyl)dipropionic Acid Derivatives as a Promising Scaffold Against Drug-Resistant Pathogens and Chemotherapy-Resistant Cancer.

Povilas Kavaliauskas, Waldo Acevedo, Eglė Mickevičiūtė, Ramunė Grigalevičiūtė, Birutė Grybaitė, Birutė Sapijanskaitė-Banevič, Guoda Pranaitytė, Vidmantas Petraitis, Rūta Petraitienė, Vytautas Mickevičius

Abstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Povilas KavaliauskasDepartment of Organic Chemistry, Kaunas University of Technology, LT-50254 Kaunas, Lithuania.
Waldo AcevedoInstituto de Química, Facultad de Ciencias, Pontificia Universidad Católica de Valparaíso, Valparaíso 2373223, Chile.ORCID 0000-0002-1182-0253
Eglė MickevičiūtėDepartment of Information Systems, Kaunas University of Technology, LT-51368 Kaunas, Lithuania.
Ramunė GrigalevičiūtėBiological Research Center, Lithuanian University of Health Sciences, Tilzes Street 18, LT-47181 Kaunas, Lithuania.ORCID 0009-0005-8723-9034
Birutė GrybaitėDepartment of Organic Chemistry, Kaunas University of Technology, LT-50254 Kaunas, Lithuania.ORCID 0000-0003-0982-1342
Birutė Sapijanskaitė-BanevičDepartment of Organic Chemistry, Kaunas University of Technology, LT-50254 Kaunas, Lithuania.
Guoda PranaitytėDepartment of Organic Chemistry, Kaunas University of Technology, LT-50254 Kaunas, Lithuania.
Vidmantas PetraitisCenter for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ 07110, USA.ORCID 0000-0001-6811-4467
Rūta PetraitienėCenter for Discovery and Innovation, Hackensack Meridian Health, Nutley, NJ 07110, USA.
Vytautas MickevičiusDepartment of Organic Chemistry, Kaunas University of Technology, LT-50254 Kaunas, Lithuania.ORCID 0000-0002-9961-2941

Funding

HPC OCÉANO (FONDEQUIP Nº EQM170214) and the supercomputing infrastructure of the NLHPC HPC OCÉANO (FONDEQUIP Nº EQM170214) and the supercomputing infrastructure of the NLHPC (CCSS21000)
6 · The paper itself

Abstract

The synthesis and antimicrobial and anticancer activity of 3,3'-((3-hydroxyphenyl)azanediyl)dipropionic acid derivatives (

Indexed as

Anti-Bacterial AgentsAntineoplastic AgentsDrug Resistance, BacterialDrug Resistance, NeoplasmPropionatesCell Line, TumorCell ProliferationEnterococcus faecalisHEK293 CellsHumansMicrobial Sensitivity TestsStaphylococcus aureusStructure-Activity RelationshipAnti-Bacterial AgentsAntineoplastic AgentsPropionates3,3′-((3-hydroxyphenyl)azanediyl)dipropionic acidantimicrobial activityc-METhead and neck cancerHER2multidrug-resistant pathogensβ-amino acids derivatives

Identifiers

PMID40430804
PMCPMC12115217

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.