Evidence map›Paper›PMID 40430712›Full record

ReviewPolymers2025

A Scoping Review of Vitamins Detection Using Electrochemically Polymerised, Molecularly Imprinted Polymers.

Mohd Azerulazree Jamilan, Balqis Kamarudin, Zainiharyati Mohd Zain, Kavirajaa Pandian Sambasevam, Faizatul Shimal Mehamod, Mohd Fairulnizal Md Noh

Abstract readReview
In one paragraph

Review in Polymers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mohd Azerulazree JamilanNutrition, Metabolism & Cardiovascular Research Centre, Institute for Medical Research, National Institute of Health, Ministry of Health Malaysia, No. 1, Jalan Setia Murni U13/52, Setia Alam, Shah Alam 40170, Selangor, Malaysia.ORCID 0000-0003-3776-4365
Balqis KamarudinNutrition, Metabolism & Cardiovascular Research Centre, Institute for Medical Research, National Institute of Health, Ministry of Health Malaysia, No. 1, Jalan Setia Murni U13/52, Setia Alam, Shah Alam 40170, Selangor, Malaysia.
Zainiharyati Mohd ZainElectrochemical Material and Sensors (EMaS) Research Group, Faculty of Applied Sciences, Universiti Teknologi MARA, Shah Alam 40450, Selangor, Malaysia.
Kavirajaa Pandian SambasevamElectrochemical Material and Sensors (EMaS) Research Group, Faculty of Applied Sciences, Universiti Teknologi MARA, Shah Alam 40450, Selangor, Malaysia.ORCID 0000-0003-4739-3916
Faizatul Shimal MehamodAdvanced Nano Materials (ANoMA) Research Group, Faculty of Science and Marine Environment, Universiti Malaysia Terengganu, Kuala Nerus 21030, Terengganu, Malaysia.
Mohd Fairulnizal Md NohNutrition, Metabolism & Cardiovascular Research Centre, Institute for Medical Research, National Institute of Health, Ministry of Health Malaysia, No. 1, Jalan Setia Murni U13/52, Setia Alam, Shah Alam 40170, Selangor, Malaysia.ORCID 0000-0001-6960-0774

Funding

Ministry of Health Malaysia NMRR ID-22-02161-STX
6 · The paper itself

Abstract

Vitamins are crucial micro-nutrients for overall well-being, making continuous monitoring essential. There are demands to provide an alternative detection, especially using a portable detection or a point-of-care-testing (POCT) device. One promising approach is employing an in situ electro-polymerised MIP (eMIP), which offers a straightforward polymerisation technique on screen-printed electrodes (SPEs). Here, we report a review based on three databases (PubMed, Scopus, and Web of Science) from 2014 to 2024 using medical subject heading (MeSH) terms "electrochemical polymerisation" OR "electropolymerisation" crossed with the terms "molecularly imprinted polymer" AND "vitamin A" OR "vitamin D" OR "vitamin E" OR "vitamin K" OR "fat soluble vitamin" OR "vitamin B" OR "vitamin C" OR "water soluble vitamin". The resulting 12 articles covered the detection of vitamins in ascorbic acid, riboflavin, cholecalciferol, calcifediol, and menadione using monomers of catechol (CAT), 3,4-ethylenedioxythiophene (EDOT), o-aminophenol (oAP), o-phenylenediamine (oPD), pyrrole, p-aminophenol (pAP), p-phenylenediamine (pPD), or resorcinol (RES), using common bare electrodes including graphite rod electrode (GRE), glassy carbon electrode (GCE), gold electrode (GE), and screen-printed carbon electrode (SPCE). The most common electrochemical detections were differential pulse voltammetry (DPV) and linear sweep voltammetry (LSV). The imprinting factor (IF) of the eMIP-modified electrodes were from 1.6 to 21.0, whereas the cross-reactivity was from 0.0% to 29.9%. Several types of food and biological samples were tested, such as supplement tablets, poultry and pharmaceutical drugs, soft drinks, beverages, milk, infant formula, human and calf serum, and human plasma. However, more discoveries and development of detection methods needs to be performed, especially for the vitamins that have not been studied yet. This will allow the improvement in the application of eMIPs on portable-based detection and POCT devices.

Indexed as

electrochemical detectioneMIPfat-soluble vitaminin situ electro-polymerisationwater-soluble vitamin

Identifiers

PMID40430712
PMCPMC12115226

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.