Evidence map›Paper›PMID 40430509›Full record

ReviewPharmaceuticals (Basel, Switzerland)2025

Exploring the Potential of s-Triazine Derivatives as Novel Antifungal Agents: A Review.

Haoyan Liao, Menglu Liu, Mengyuan Wang, Dazhi Zhang, Yumeng Hao, Fei Xie

Abstract readReview
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Haoyan LiaoStudent Bridge, College of Basic Medical Sciences, Naval Medical University, No. 800 Xiangyin Road, Shanghai 200433, China.
Menglu LiuStudent Bridge, College of Basic Medical Sciences, Naval Medical University, No. 800 Xiangyin Road, Shanghai 200433, China.
Mengyuan WangDepartment of Organic Chemistry, School of Pharmacy, Naval Medical University, No. 325 Guohe Road, Shanghai 200433, China.
Dazhi ZhangDepartment of Organic Chemistry, School of Pharmacy, Naval Medical University, No. 325 Guohe Road, Shanghai 200433, China.
Yumeng HaoDepartment of Organic Chemistry, School of Pharmacy, Naval Medical University, No. 325 Guohe Road, Shanghai 200433, China.
Fei XieDepartment of Organic Chemistry, School of Pharmacy, Naval Medical University, No. 325 Guohe Road, Shanghai 200433, China.ORCID 0000-0002-0427-3802

Funding

National Natural Science Foundation of China 82304302Naval Key Discipline Professional Project 2024-HJZDXK-JS-08Naval Medical University Undergraduates' Innovation and Practice Training Programs FH2024212Naval Medical University Young Research Fellowship Grant 2024QN013
6 · The paper itself

Abstract

The growing incidence and prevalence of invasive fungal infections (IFIs) and the emergence of antimicrobial resistance compound clinical antifungal therapies. Given the significant threat posed by IFIs and the limits of the current antifungal agents, the search for novel, effective therapeutic options remains a compelling area of antifungal drug discovery. The s-triazine (1,3,5-triazine) scaffold, renowned for its structural versatility, ease of functionalization, and diverse biological profiles, has been extensively studied in medical chemistry. Driven by this privileged structure, several s-triazine derivatives have been synthesized through molecular hybridization and screened for their antifungal activities. Some of them demonstrated potent efficacy against pathogenic fungi, including

Indexed as

antifungal activityheterocyclic compoundminimum inhibitory concentrations-triazine derivatives

Identifiers

PMID40430509
PMCPMC12115033

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.