Evidence map›Paper›PMID 40430480›Full record

ArticlePharmaceuticals (Basel, Switzerland)2025

Isoetin from Isoetaceae Exhibits Superior Pentatransferase Inhibition in Breast Cancer: Comparative Computational Profiling with FDA-Approved Tucatinib.

Abdulaziz H Al Khzem, Mansour S Alturki, Ohood K Almuzaini, Saad M Wali, Mohammed Almaghrabi, Mohammed F Aldawsari, Maram H Abduljabbar, Reem M Alnemari, Atiah H Almalki, Thankhoe A Rants'o

Abstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Abdulaziz H Al KhzemDepartment of Pharmaceutical Chemistry, College of Pharmacy, Imam Abdulrahman Bin Faisal University, P.O. Box 1982, Dammam 31441, Saudi Arabia.ORCID 0009-0004-0079-8646
Mansour S AlturkiDepartment of Pharmaceutical Chemistry, College of Pharmacy, Imam Abdulrahman Bin Faisal University, P.O. Box 1982, Dammam 31441, Saudi Arabia.ORCID 0000-0001-7702-9379
Ohood K AlmuzainiDepartment of Pharmacology and Toxicology, College of Pharmacy, Umm Al-Qura University, Makkah 24342, Saudi Arabia.ORCID 0009-0000-6100-6658
Saad M WaliDepartment of Pharmacology and Toxicology, College of Pharmacy, Umm Al-Qura University, Makkah 24342, Saudi Arabia.ORCID 0009-0006-0080-4799
Mohammed AlmaghrabiDepartment of Pharmacognosy and Pharmaceutical Chemistry, Faculty of Pharmacy, Taibah University, Al Madinah Al Munawarah 30001, Saudi Arabia.ORCID 0000-0003-4929-7071
Mohammed F AldawsariDepartment of Pharmaceutics, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj 11942, Saudi Arabia.ORCID 0000-0003-1298-4863
Maram H AbduljabbarDepartment of Pharmacology and Toxicology, College of Pharmacy, Taif University, Taif 21944, Saudi Arabia.ORCID 0000-0002-3808-548X
Reem M AlnemariDepartment of Pharmaceutics and Pharmaceutical Technology, College of Pharmacy, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia.ORCID 0000-0002-5028-8386
Atiah H AlmalkiDepartment of Pharmaceutical Chemistry, College of Pharmacy, Taif University, P.O. Box 11099, Taif 21944, Saudi Arabia.ORCID 0000-0003-4379-7024
Thankhoe A Rants'oDepartment of Pharmacology and Toxicology, College of Pharmacy, University of Utah, Salt Lake City, UT 84112, USA.ORCID 0000-0001-8585-0888

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

binding free energybreast cancer resistanceIsoetintucatinibWaterMap

Identifiers

PMID40430480
PMCPMC12115012

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.