ArticlePharmaceuticals (Basel, Switzerland)2025
Fructose-1,6-Bisphosphate Reduces Chronic Constriction Injury Neuropathic Pain in Mice by Targeting Dorsal Root Ganglia Nociceptive Neuron Activation.
Amanda Martins Dionisio, Paula de Azevedo Oliveira Milanez, Ana Carla Zarpelon-Schutz, Sandra Satie Mizokami, Mariana Marques Bertozzi, Kelly Megumi Yaekashi, Doumit Camilios-Neto, Sergio Marques Borghi, Rubia Casagrande, Waldiceu A Verri
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In one paragraphArticle in Pharmaceuticals (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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0citing papers in PubMed
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
10 authors.
Amanda Martins DionisioLaboratory of Pain, Inflammation, Neuropathy, and Cancer, Department of Immunology, Parasitology and General Pathology, Center of Biological Sciences, Londrina State University, Londrina 86057-970, PR, Brazil.ORCID 0000-0003-1542-4386 Paula de Azevedo Oliveira MilanezLaboratory of Pain, Inflammation, Neuropathy, and Cancer, Department of Immunology, Parasitology and General Pathology, Center of Biological Sciences, Londrina State University, Londrina 86057-970, PR, Brazil.
Ana Carla Zarpelon-SchutzLaboratory of Pain, Inflammation, Neuropathy, and Cancer, Department of Immunology, Parasitology and General Pathology, Center of Biological Sciences, Londrina State University, Londrina 86057-970, PR, Brazil.ORCID 0000-0002-8320-3633 Sandra Satie MizokamiLaboratory of Pain, Inflammation, Neuropathy, and Cancer, Department of Immunology, Parasitology and General Pathology, Center of Biological Sciences, Londrina State University, Londrina 86057-970, PR, Brazil.
Mariana Marques BertozziLaboratory of Pain, Inflammation, Neuropathy, and Cancer, Department of Immunology, Parasitology and General Pathology, Center of Biological Sciences, Londrina State University, Londrina 86057-970, PR, Brazil.ORCID 0000-0002-0551-4313 Kelly Megumi YaekashiLaboratory of Pain, Inflammation, Neuropathy, and Cancer, Department of Immunology, Parasitology and General Pathology, Center of Biological Sciences, Londrina State University, Londrina 86057-970, PR, Brazil.ORCID 0000-0002-4047-3975 Doumit Camilios-NetoDepartment of Biochemistry and Biotechnology, Centre of Exact Sciences, Londrina State University, Londrina 86057-970, PR, Brazil.ORCID 0000-0002-1986-658X Sergio Marques BorghiLaboratory of Pain, Inflammation, Neuropathy, and Cancer, Department of Immunology, Parasitology and General Pathology, Center of Biological Sciences, Londrina State University, Londrina 86057-970, PR, Brazil.ORCID 0000-0002-6978-7505 Rubia CasagrandeDepartment of Pharmaceutical Sciences, Center of Health Science, Londrina State University, Londrina 86038-440, PR, Brazil.ORCID 0000-0002-2296-1668 Waldiceu A VerriLaboratory of Pain, Inflammation, Neuropathy, and Cancer, Department of Immunology, Parasitology and General Pathology, Center of Biological Sciences, Londrina State University, Londrina 86057-970, PR, Brazil.ORCID 0000-0003-2756-9283 Funding
Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) #309633/2021-4Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) 405027/2021-4Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) #427946/2018-2Fundação Araucária #276/2022-PBAFundação Nacional de Desenvolvimento do Ensino Superior Particular (FUNADESP) #5301159
6 · The paper itselfAbstract
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Indexed as
adenosine A1 receptoradenosine A2A receptorfructose-1,6-bisphosphatemouseneuropathic painNO/cGMP/PKG/K+ATP signaling pathway
Identifiers
PMID40430479
PMCPMC12114996
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