Evidence map›Paper›PMID 40430429›Full record

ArticlePharmaceuticals (Basel, Switzerland)2025

Structural Activity Relationship Analysis of New Diphenyl PFI-3 Analogues Targeting for the Treatment of Glioblastoma.

Dong-Jin Hwang, Chuanhe Yang, Yinan Wang, Hannah Kelso, Satyanarayana Pochampally, Lawrence M Pfeffer, Duane D Miller

Abstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Dong-Jin HwangDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee Health Science Center, Memphis, TN 38163, USA.ORCID 0000-0002-0055-1916
Chuanhe YangDepartment of Pathology and Laboratory Medicine, College of Medicine, University of Tennessee Health Science Center, Memphis, TN 38103, USA.
Yinan WangDepartment of Pathology and Laboratory Medicine, College of Medicine, University of Tennessee Health Science Center, Memphis, TN 38103, USA.
Hannah KelsoDepartment of Pathology and Laboratory Medicine, College of Medicine, University of Tennessee Health Science Center, Memphis, TN 38103, USA.
Satyanarayana PochampallyDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee Health Science Center, Memphis, TN 38163, USA.
Lawrence M PfefferDepartment of Pathology and Laboratory Medicine, College of Medicine, University of Tennessee Health Science Center, Memphis, TN 38103, USA.ORCID 0000-0003-2809-1234
Duane D MillerDepartment of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee Health Science Center, Memphis, TN 38163, USA.ORCID 0000-0002-6093-0985

Funding

Therapeutic targeting of the SWI/SNF chromatin remodeler to regulate GBM chemosensitivityR01CA281977 · NCI · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI DUANE D MILLER, LAWRENCE MARC PFEFFER · 2023 to 2026
$2.0M
NCI NIH HHS R01 CA281977NIH HHS 1R01CA281977-2the National Cancer Institute (NCI) to L.M.P. and D.D.M. CA-281977
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

anti-GBM activitybromodomainglioblastoma (GBM)PFI-3 analogstructure–activity relationship (SAR)temozolomide (TMZ)therapeutic enhancing drug (TED)

Identifiers

PMID40430429
PMCPMC12114682

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.