Evidence map›Paper›PMID 40430326›Full record

ArticleMolecules (Basel, Switzerland)2025

Straightforward Access to Polyfunctionalized δ-Lactams via Domino Aza-Michael/Thia-Michael/Aldol Sequence.

Axelle Genty, Ismail Alahyen, Marie-José Tranchant, Jérôme Lhoste, Vincent Dalla, Catherine Taillier, Sébastien Comesse

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Axelle GentyUniversité Le Havre Normandie, Normandie Université, URCOM UR 3221, F-76600 Le Havre, France.
Ismail AlahyenUniversité Le Havre Normandie, Normandie Université, URCOM UR 3221, F-76600 Le Havre, France.
Marie-José TranchantUniversité Le Havre Normandie, Normandie Université, URCOM UR 3221, F-76600 Le Havre, France.
Jérôme LhosteIMMM, UMR 6283 CNRS, Le Mans Université, F-72085 Le Mans, France.ORCID 0000-0002-4570-6459
Vincent DallaUniversité Le Havre Normandie, Normandie Université, URCOM UR 3221, F-76600 Le Havre, France.
Catherine TaillierUniversité Le Havre Normandie, Normandie Université, URCOM UR 3221, F-76600 Le Havre, France.ORCID 0000-0001-9277-0130
Sébastien ComesseUniversité Le Havre Normandie, Normandie Université, URCOM UR 3221, F-76600 Le Havre, France.ORCID 0000-0002-0794-8115

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Domino reactions are powerful tools for the straightforward synthesis of complex molecules with a particular emphasis on functionalized azacycles. We report a contribution in this field, implemented via a new thia-Michael/aldol sequence between readily accessible

Indexed as

aldolaza–Michaeldomino reactionN-alkoxyacrylamidesstereoselective synthesisthia–Michaelδ-lactams

Identifiers

PMID40430326
PMCPMC12114351

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.