Evidence map›Paper›PMID 40430298›Full record

ArticleMolecules (Basel, Switzerland)2025

Interactions of Ligand, Aptamer, and Complementary Oligonucleotide: Studying Impacts of Na

Alexey V Samokhvalov, Oksana G Maksimenko, Sergei A Eremin, Anatoly V Zherdev, Boris B Dzantiev

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alexey V SamokhvalovA.N. Bach Institute of Biochemistry, Research Center of Biotechnology, Russian Academy of Sciences, Moscow 119071, Russia.
Oksana G MaksimenkoInstitute of Gene Biology, Russian Academy of Sciences, Moscow 119334, Russia.ORCID 0000-0003-3502-0303
Sergei A EreminFaculty of Chemistry, M.V. Lomonosov Moscow State University, Moscow 119991, Russia.
Anatoly V ZherdevA.N. Bach Institute of Biochemistry, Research Center of Biotechnology, Russian Academy of Sciences, Moscow 119071, Russia.ORCID 0000-0003-3008-2839
Boris B DzantievA.N. Bach Institute of Biochemistry, Research Center of Biotechnology, Russian Academy of Sciences, Moscow 119071, Russia.ORCID 0000-0003-4008-4918

Funding

Russian Science Foundation 23-74-01080
6 · The paper itself

Abstract

The effects of magnesium and sodium on the interactions between aptamer, its specific ligand, and short complementary oligonucleotides (cDNAs) differing in affinity of their binding with the aptamer were studied. Aflatoxin B1 (AFB1) and AFB1-binding aptamer were used in the study. Dependencies for the aptamer binding with the fluorophore-labeled AFB1 under varied concentrations of the cations were obtained using fluorescence anisotropy measurements. The increase of the aptamer affinity to AFB1 in the presence of cations was demonstrated using fluorescence anisotropy and isothermal calorimetry. The collected data indicate that 300 mM Mg

Indexed as

Aflatoxin B1Aptamers, NucleotideFluorescence Resonance Energy TransferMagnesiumOligonucleotidesSodiumCationsLigandsAflatoxin B1Aptamers, NucleotideCationsLigandsMagnesiumOligonucleotidesSodiumaptamerscomplexes of nucleic acidsfluorescence polarizationForster resonance energy transferisothermal titration calorimetrymetal cationsmycotoxinstarget-induced strand displacement

Identifiers

PMID40430298
PMCPMC12114067

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.