Evidence map›Paper›PMID 40430211›Full record

ArticleLife (Basel, Switzerland)2025

Clinical and Paraclinical Peculiarities of SARS-CoV-2 and Influenza Infections in Children: A Comparative Study.

Maria Oana Săsăran, Carmen Viorica Muntean, Andreea Bianca Stoica, Carmen Schwesig, Anca Meda Văsieșiu, Anca Doina Pleșca, Cristina Oana Mărginean

Abstract read
In one paragraph

Article in Life (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Maria Oana SăsăranDepartment of Pediatrics 3, "George Emil Palade" University of Medicine, Pharmacy, Science, and Technology of Targu Mures, Gheorghe Marinescu Street No. 38, 540136 Targu Mures, Romania.ORCID 0000-0001-8156-7460
Carmen Viorica MunteanDepartment of Pediatrics 1, "George Emil Palade" University of Medicine, Pharmacy, Science, and Technology of Targu Mures, Gheorghe Marinescu Street No. 38, 540136 Targu Mures, Romania.ORCID 0000-0002-8056-1339
Andreea Bianca StoicaDepartment of Pediatrics 1, "George Emil Palade" University of Medicine, Pharmacy, Science, and Technology of Targu Mures, Gheorghe Marinescu Street No. 38, 540136 Targu Mures, Romania.
Carmen SchwesigDepartment of Internal Medicine, Weser-Egge Clinic-St. Josef Hospital Bad Driburg, Elmarstrasse No. 38, 33014 Bad Driburg, Germany.
Anca Meda VăsieșiuDepartment of Infectious Disease, "George Emil Palade" University of Medicine, Pharmacy, Science, and Technology of Targu Mures, Gheorghe Marinescu Street No. 38, 540136 Targu Mures, Romania.ORCID 0000-0003-2880-4337
Anca Doina PleșcaDepartment of Pediatrics, Carol Davila University of Medicine and Pharmacy, Boulevard Eroii Sanitari No. 8, 050474 Bucharest, Romania.ORCID 0000-0002-8849-6834
Cristina Oana MărgineanDepartment of Pediatrics 1, "George Emil Palade" University of Medicine, Pharmacy, Science, and Technology of Targu Mures, Gheorghe Marinescu Street No. 38, 540136 Targu Mures, Romania.ORCID 0000-0003-2119-1726

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSARS-CoV-2 and influenza can present with similar clinical pictures in children, with symptoms and paraclinical particularities which might aid in the differentiation of the two entities and which can be suggestive of various complications. The present study aims to identify clinical and paraclinical differences between pediatric SARS-CoV-2 and influenza infection and to assess the utility of hematological parameters for prediction of their related complications.

methodsIn this study, 266 children were retrospectively enrolled, divided into two groups: 129 children diagnosed with SARS-CoV-2 infection and 137 children infected with influenza. In each case, particular symptoms were recorded, as well as hospitalization duration, pediatric intensive care unit (PICU) admission or O

resultsSARS-CoV-2 infections were more commonly associated with digestive symptoms, whereas influenza infections implied longer hospital stays and higher likelihood of PICU admission necessity. Monocytes and lymphocyte/monocyte ratios (LMRs) were significantly higher in the SARS-CoV-2 group (

conclusionsAccording to the study, monocyte levels and LMR can aid in the distinction of pediatric SARS-CoV-2 and influenza infections and LMR and NLR can be used particularly as predictors of complicated course of these infections.

Indexed as

childrenhematological parametersinfluenza infectionSARS-CoV-2 infection

Identifiers

PMID40430211
PMCPMC12113390

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.