ArticleLife (Basel, Switzerland)2025
Comparative Effects of Red and Blue LED Light on Melatonin Levels During Three-Hour Exposure in Healthy Adults.
Article in Life (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Vitamin D as a Regulator of the Biological Clock-Implications for Circadian-Metabolic Dysregulation.International journal of molecular sciences · 2026Review
- Nutritional adaptation to circadian misalignment: implications for musculoskeletal health in modern lifestyles.Frontiers in nutrition · 2026Review
- Repeated low-intensity red light combined with defocus-incorporated multiple segments (DIMS) spectacles for controlling myopia progression in children.American journal of translational research · 2026Article
- From nighttime light exposure to menstrual health: a critical review of evidence, mechanisms, and nursing interventions.Frontiers in reproductive health · 2026Review
- The role of FoMO and nomophobia in explaining the relationship between doomscrolling and poor sleep quality.BMC psychology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Circadian rhythms, essential for regulating human physiology and behavior, are influenced by light exposure, particularly at night. This study examined the impact of red (631 nm) and blue (464 nm) LED light on melatonin secretion, a key circadian marker. Twelve participants aged 19-55 years were exposed to red and blue light for three hours (9:00 p.m.-midnight), with hourly saliva samples analyzed via ELISA to track melatonin levels. Initially, melatonin levels were comparable under both light conditions. After one hour, both lights suppressed melatonin, but differences emerged after two hours: blue light-maintained suppression, with levels at 7.5 pg/mL, while red light allowed recovery to 26.0 pg/mL (
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.