Evidence map›Paper›PMID 40430085›Full record

ArticleInternational journal of molecular sciences2025

Cannabidiolic Acid Rescues Deficits in Hippocampal Long-Term Potentiation in Models of Alzheimer's Disease: An Electrophysiological and Proteomic Analysis.

Beatriz Gil, Mairéad Sullivan, Caitriona Scaife, Jeffrey C Glennon, Caroline Herron

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Beatriz GilSchool of Biomolecular and Biomedical Sciences, University College Dublin, Conway Institute, Dublin 4, Ireland.
Mairéad SullivanSchool of Medicine and Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Conway Institute, Dublin 4, Ireland.
Caitriona ScaifeConway Institute, University College, Dublin 4, Ireland.ORCID 0000-0002-7463-0676
Jeffrey C GlennonSchool of Medicine and Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Conway Institute, Dublin 4, Ireland.ORCID 0000-0002-2371-0422
Caroline HerronSchool of Biomolecular and Biomedical Sciences, University College Dublin, Conway Institute, Dublin 4, Ireland.

Funding

Jazz Pharmaceuticals UK and University College Dublin N/A
6 · The paper itself

Abstract

In this study, we have examined the neuroprotective effects of cannabidiolic acid (CBDA) in models of Alzheimer's disease (AD). We used in vitro electrophysiological recording in hippocampal slices and performed proteomic analysis of cortical tissue from APP

Indexed as

Alzheimer DiseaseHippocampusLong-Term PotentiationNeuroprotective AgentsAmyloid beta-PeptidesAmyloid beta-Protein PrecursorAnimalsDisease Models, AnimalMaleMiceMice, Inbred C57BLMice, TransgenicProteomicsAmyloid beta-PeptidesAmyloid beta-Protein PrecursorNeuroprotective AgentsAlzheimer’s diseaseAPP/PS1CBDAelectrophysiologylong-term potentiationproteomicssynaptic plasticity

Identifiers

PMID40430085
PMCPMC12112199

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.