Evidence map›Paper›PMID 40430074›Full record

ArticleInternational journal of molecular sciences2025

Telomere Length, Oxidative Stress Markers, and Related miRNAs in Non-Invasive Samples of Mild COVID-19 Cases.

Angélica Domínguez-de-Barros, Candela Sirvent-Blanco, Omar García-Pérez, Malena Gajate-Arenas, Alma García-Ramos, Claudia Migliazzo, José E Piñero, Jacob Lorenzo-Morales, Elizabeth Córdoba-Lanús

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Angélica Domínguez-de-BarrosInstituto Universitario de Enfermedades Tropicales y Salud Pública de Canarias (IUETSPC), Universidad de La Laguna, 38029 La Laguna, Tenerife, Spain.ORCID 0009-0008-8562-6403
Candela Sirvent-BlancoInstituto Universitario de Enfermedades Tropicales y Salud Pública de Canarias (IUETSPC), Universidad de La Laguna, 38029 La Laguna, Tenerife, Spain.
Omar García-PérezInstituto Universitario de Enfermedades Tropicales y Salud Pública de Canarias (IUETSPC), Universidad de La Laguna, 38029 La Laguna, Tenerife, Spain.
Malena Gajate-ArenasInstituto Universitario de Enfermedades Tropicales y Salud Pública de Canarias (IUETSPC), Universidad de La Laguna, 38029 La Laguna, Tenerife, Spain.
Alma García-RamosInstituto Universitario de Enfermedades Tropicales y Salud Pública de Canarias (IUETSPC), Universidad de La Laguna, 38029 La Laguna, Tenerife, Spain.
Claudia MigliazzoDipartmento di Scienze e Tecnologie Biologiche Chimiche e Farmaceutiche, Universita' Degli Studi di Palermo, 90133 Palermo, Italy.ORCID 0009-0002-0556-0413
José E PiñeroInstituto Universitario de Enfermedades Tropicales y Salud Pública de Canarias (IUETSPC), Universidad de La Laguna, 38029 La Laguna, Tenerife, Spain.ORCID 0000-0001-6233-8224
Jacob Lorenzo-MoralesInstituto Universitario de Enfermedades Tropicales y Salud Pública de Canarias (IUETSPC), Universidad de La Laguna, 38029 La Laguna, Tenerife, Spain.
Elizabeth Córdoba-LanúsInstituto Universitario de Enfermedades Tropicales y Salud Pública de Canarias (IUETSPC), Universidad de La Laguna, 38029 La Laguna, Tenerife, Spain.ORCID 0000-0001-5534-8280

Funding

Agencia Canaria de Investigación, Innovación y Sociedad de la Información ACIISI 2024Cabildo Insular de Tenerife 2023-2028, PI-CC202302222, Cabildo.23 and PI-2024/0002347Consorcio Centro de Investigación Biomédica (CIBER) de Enfermedades Infecciosas (CIBERINFEC) (CB21/13/00100Ministerio de Sanidad, Spain. Ministerio de Sanidad, Spain.
6 · The paper itself

Abstract

Oxidative stress and inflammation influence immune response and epigenetic mechanisms in infectious diseases. In mild COVID-19, host-encoded miRNA profiles remain underexplored, although they reveal mechanistic insights into disease pathogenesis. This study evaluated ageing and oxidative stress biomarkers (telomere length (TL), TBARS, 8-OHdG, and circulating related-miRNA expression) in 75 mild cases and 30 non-COVID-19 controls. TL correlated with age (R = -0.384,

Indexed as

COVID-19MicroRNAsOxidative StressTelomereAdultAgingBiomarkersFemaleGene Expression RegulationHumansMaleSeverity of Illness IndexBiomarkersMicroRNAsbiomarkersinfection responsemicroRNAsoxidative stressSARS-CoV2

Identifiers

PMID40430074
PMCPMC12111949

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.