Evidence map›Paper›PMID 40430031›Full record

ArticleInternational journal of molecular sciences2025

Mass Spectrometric ITEM-FOUR Analysis Reveals Coding Single-Nucleotide Polymorphisms in Human Cardiac Troponin T That Evade Detection by Sandwich ELISAs Which Use Monoclonal Antibodies M7 and M11.7 from the Elecsys Troponin T

Kristjan Kormann, Manuela Ruß, Claudia Röwer, Cornelia Koy, Michael O Glocker

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kristjan KormannProteome Center Rostock University Medicine and Natural Science Faculty, University of Rostock, Schillingallee 69, 18057 Rostock, Germany.
Manuela RußProteome Center Rostock University Medicine and Natural Science Faculty, University of Rostock, Schillingallee 69, 18057 Rostock, Germany.ORCID 0000-0001-5550-4618
Claudia RöwerProteome Center Rostock University Medicine and Natural Science Faculty, University of Rostock, Schillingallee 69, 18057 Rostock, Germany.
Cornelia KoyProteome Center Rostock University Medicine and Natural Science Faculty, University of Rostock, Schillingallee 69, 18057 Rostock, Germany.ORCID 0000-0002-3475-1799
Michael O GlockerProteome Center Rostock University Medicine and Natural Science Faculty, University of Rostock, Schillingallee 69, 18057 Rostock, Germany.ORCID 0000-0001-9190-482X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immunoassays for cardiac troponin, such as the Elecsys

Indexed as

Antibodies, MonoclonalMass SpectrometryPolymorphism, Single NucleotideTroponin TEpitopesHumansImmunoassayMyocardial InfarctionAntibodies, MonoclonalEpitopesTroponin Thuman troponin Timmune complex analysisITEM-FOURmyocardial infarctionnano-ESI mass spectrometrysingle-amino-acid polymorphismsingle-nucleotide polymorphism

Identifiers

PMID40430031
PMCPMC12112476

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.