Evidence map›Paper›PMID 40429982›Full record

ArticleInternational journal of molecular sciences2025

Structural Characterisation of TetR/AcrR Regulators in

Karla Leal, Juan Machuca, Humberto Gajardo, Matías Palma, María José Contreras, Kattia Nuñez-Montero, Álvaro Gutiérrez, Leticia Barrientos

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Actinomycin Analogs from Soil-DerivedLife (Basel, Switzerland) · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Karla LealFacultad de Ingeniería, Instituto de Ciencias Aplicadas, Universidad Autónoma de Chile, Temuco 4780000, Chile.ORCID 0000-0001-7526-464X
Juan MachucaFacultad de Ciencias de la Salud, Instituto de Ciencias Biomédicas, Universidad Autónoma de Chile, Temuco 4780000, Chile.
Humberto GajardoFacultad de Ingeniería, Instituto de Ciencias Aplicadas, Universidad Autónoma de Chile, Temuco 4780000, Chile.ORCID 0000-0002-5754-9796
Matías PalmaFacultad de Ingeniería, Instituto de Ciencias Aplicadas, Universidad Autónoma de Chile, Temuco 4780000, Chile.
María José ContrerasFacultad de Ingeniería, Instituto de Ciencias Aplicadas, Universidad Autónoma de Chile, Temuco 4780000, Chile.
Kattia Nuñez-MonteroFacultad de Ciencias de la Salud, Instituto de Ciencias Aplicadas, Universidad Autónoma de Chile, Temuco 4780000, Chile.ORCID 0000-0002-8629-5107
Álvaro GutiérrezLaboratory of Integrative Biology (LIBi), Millennium Institute on Immunology and Immunotherapy, Centro de Excelencia en Medicina Traslacional (CEMT), Scientific and Technological Bioresource Nucleus (BI-REN), Universidad de La Frontera, Temuco 4810296, Chile.
Leticia BarrientosFacultad de Ciencias de la Salud, Instituto de Ciencias Aplicadas, Universidad Autónoma de Chile, Temuco 4780000, Chile.ORCID 0000-0002-5344-054X

Funding

Fondecyt Iniciación 11230475Fondecyt Iniciación 11240632Fondecyt Regular 1210563
6 · The paper itself

Abstract

The growing threat of antimicrobial resistance has intensified the search for new bioactive compounds, particularly in extreme environments such as Antarctica.

Indexed as

Bacterial ProteinsCRISPR-Cas SystemsDactinomycinStreptomycesTranscription FactorsAnti-Bacterial AgentsBiosynthetic PathwaysGene Expression Regulation, BacterialMolecular Dynamics SimulationMultigene FamilyAnti-Bacterial AgentsBacterial ProteinsDactinomycinTranscription FactorsAntarctic Streptomycesbiosynthetic gene clustersCRISPR-based activationmolecular dynamics simulation

Identifiers

PMID40429982
PMCPMC12112392

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.